Protein: EREP3
Protein ENTREP3 (Endosomal transmembrane epsin interactor 3) (Protein COTE1)

Gene: EREP3, ENTREP3
Organism: Homo sapiens
Interactions: 139
UniProt ID: P81408

Gene Ontology (top 5):
GO:0016020 - membrane
GO:0050699 - WW domain binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1010505

BT2A2
Butyrophilin subfamily 2 member A2

2

1

High-throughput

0.705

High

1010516

ITCH
E3 ubiquitin-protein ligase Itchy homolog

4

15

High-throughput

0.691

High

821708

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.679

High

1010552

RHBD3
Rhomboid domain-containing protein 3

3

4

High-throughput

0.667

High

1010540

WWOX
WW domain-containing oxidoreductase

5

1

Small-scale

0.652

High

212386

SPIT2
Kunitz-type protease inhibitor 2

3

0

High-throughput

0.638

High

861564

NEDD4
E3 ubiquitin-protein ligase NEDD4

4

15

High-throughput

0.630

High

1010495

AN13A
Ankyrin repeat domain-containing protein 13A

4

3

High-throughput

0.630

High

1010517

NED4L
E3 ubiquitin-protein ligase NEDD4-like

4

15

High-throughput

0.630

High

1010530

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

4

15

High-throughput

0.630

High

1010542

HECW2
E3 ubiquitin-protein ligase HECW2

4

15

High-throughput

0.630

High

663521

FSHR
Follicle-stimulating hormone receptor

2

1

High-throughput

0.628

High

1010523

KCNS3
Delayed-rectifier potassium channel regulatory subunit KCNS3

2

1

High-throughput

0.628

High

1010544

CLC2D
C-type lectin domain family 2 member D

2

4

High-throughput

0.628

High

1010485

AN13D
Ankyrin repeat domain-containing protein 13D

3

3

High-throughput

0.609

High

1010488

HECW1
E3 ubiquitin-protein ligase HECW1

3

15

High-throughput

0.604

High

191957

TEX28
Testis-specific protein TEX28

2

0

High-throughput

0.602

High

851108

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

2

3

High-throughput

0.601

High

1010536

ST7
Suppressor of tumorigenicity 7 protein

2

2

High-throughput

0.601

High

536248

PPAL
Lysosomal acid phosphatase

2

0

High-throughput

0.585

High

1010459

ACHD
Acetylcholine receptor subunit delta

2

3

High-throughput

0.574

High

1010521

GPR21
Probable G-protein coupled receptor 21

2

1

High-throughput

0.574

High

1010556

PCDG5
Protocadherin gamma-A5

2

2

High-throughput

0.574

High

252673

TSN3
Tetraspanin-3

2

1

High-throughput

0.558

High

1010465

HERC3
Probable E3 ubiquitin-protein ligase HERC3

2

16

High-throughput

0.558

High

1010489

BT2A1
Butyrophilin subfamily 2 member A1

1

1

High-throughput

0.553

High

1010470

HFE
Hereditary hemochromatosis protein

2

1

High-throughput

0.549

High

1010537

CUED1
CUE domain-containing protein 1

2

1

High-throughput

0.549

High

862033

YAP1
Transcriptional coactivator YAP1

2

16

High-throughput

0.543

High

62111

KLRG2
Killer cell lectin-like receptor subfamily G member 2

1

4

High-throughput

0.536

High

270147

LRP3
Low-density lipoprotein receptor-related protein 3

1

2

High-throughput

0.536

High

321758

AGRL1
Adhesion G protein-coupled receptor L1

1

1

High-throughput

0.536

High

347641

BAG3
BAG family molecular chaperone regulator 3

1

2

High-throughput

0.536

High

790147

PIGA
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A

1

1

High-throughput

0.536

High

1010461

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

1

1

High-throughput

0.536

High

1010471

PTHD3
Patched domain-containing protein 3

1

1

High-throughput

0.536

High

1010477

S27A3
Long-chain fatty acid transport protein 3

1

2

High-throughput

0.536

High

1010478

COL12
Collectin-12

1

1

High-throughput

0.536

High

1010490

LRP10
Low-density lipoprotein receptor-related protein 10

1

2

High-throughput

0.536

High

1010498

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.536

High

1010500

ST7L
Suppressor of tumorigenicity 7 protein-like

1

2

High-throughput

0.536

High

1010513

S47A1
Multidrug and toxin extrusion protein 1

1

1

High-throughput

0.536

High

1010527

ABCA2
ATP-binding cassette sub-family A member 2

1

1

High-throughput

0.536

High

1010531

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.536

High

1010533

PCX3
Pecanex-like protein 3

1

1

High-throughput

0.536

High

1010546

AMFR
E3 ubiquitin-protein ligase AMFR

1

1

High-throughput

0.536

High

1010548

S12A4
Solute carrier family 12 member 4

1

4

High-throughput

0.536

High

1010553

LRP12
Low-density lipoprotein receptor-related protein 12

1

2

High-throughput

0.536

High

1010558

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

2

High-throughput

0.536

High

161129

ABCD4
Lysosomal cobalamin transporter ABCD4

1

0

High-throughput

0.513

High

862633

UTRN
Utrophin

1

0

High-throughput

0.513

High

1010473

FND3B
Fibronectin type III domain-containing protein 3B

1

0

High-throughput

0.513

High

1010509

EDA
Ectodysplasin-A

1

0

High-throughput

0.513

High

1010551

DHRS7
Dehydrogenase/reductase SDR family member 7

1

0

High-throughput

0.513

High

294778

CAN15
Calpain-15

1

2

High-throughput

0.489

High

320657

UBXN7
UBX domain-containing protein 7

1

2

High-throughput

0.489

High

337942

CNEP1
CTD nuclear envelope phosphatase 1

1

1

High-throughput

0.489

High

1010460

TRI32
E3 ubiquitin-protein ligase TRIM32

1

1

High-throughput

0.489

High

1010469

CL12B
C-type lectin domain family 12 member B

1

3

High-throughput

0.489

High

1010476

HERC4
Probable E3 ubiquitin-protein ligase HERC4

1

18

High-throughput

0.489

High

1010481

KCNT2
Potassium channel subfamily T member 2

1

2

High-throughput

0.489

High

1010484

RN111
E3 ubiquitin-protein ligase Arkadia

1

1

High-throughput

0.489

High

1010491

T179B
Transmembrane protein 179B

1

1

High-throughput

0.489

High

1010493

TAXB1
Tax1-binding protein 1

1

4

High-throughput

0.489

High

1010497

SIDT2
SID1 transmembrane family member 2

1

1

High-throughput

0.489

High

1010501

RHBL4
Rhomboid-related protein 4

1

2

High-throughput

0.489

High

1010502

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

2

High-throughput

0.489

High

1010504

LMBR1
Limb region 1 protein homolog

1

1

High-throughput

0.489

High

1010511

RNF31
E3 ubiquitin-protein ligase RNF31

1

1

High-throughput

0.489

High

1010522

SMO
Protein smoothened

1

1

High-throughput

0.489

High

1010525

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

2

High-throughput

0.489

High

1010554

PCDGM
Protocadherin gamma-C5

1

2

High-throughput

0.489

High

1010555

PCDGL
Protocadherin gamma-C4

1

2

High-throughput

0.489

High

1010557

EPN1
Epsin-1

1

2

High-throughput

0.489

High

1010462

SNTA1
Alpha-1-syntrophin

1

1

Small-scale

0.481

High

946548

EVA1C
Protein eva-1 homolog C

1

2

High-throughput

0.479

High

536959

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

845418

PE2R3
Prostaglandin E2 receptor EP3 subtype

1

0

High-throughput

0.458

High

131944

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

15

High-throughput

0.445

High

256461

TOM1
Target of Myb1 membrane trafficking protein

1

3

High-throughput

0.445

High

1010486

TM1L2
TOM1-like protein 2

1

3

High-throughput

0.445

High

1010492

S47A2
Multidrug and toxin extrusion protein 2

1

1

High-throughput

0.445

High

1010524

S4A5
Electrogenic sodium bicarbonate cotransporter 4

1

1

High-throughput

0.445

High

1010547

MYO6
Unconventional myosin-VI

1

1

High-throughput

0.445

High

462774

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

1

High-throughput

0.439

High

455963

ASGR2
Asialoglycoprotein receptor 2

1

3

High-throughput

0.437

High

1005535

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

1

2

High-throughput

0.437

High

1010482

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1010508

5HT3C
5-hydroxytryptamine receptor 3C

1

4

High-throughput

0.437

High

1010543

ACHA9
Neuronal acetylcholine receptor subunit alpha-9

1

3

High-throughput

0.437

High

1010550

GPR52
G-protein coupled receptor 52

1

1

High-throughput

0.437

High

1010483

S49A3
Solute carrier family 49 member A3

1

0

High-throughput

0.426

High

1010507

CTL1
Choline transporter-like protein 1

1

0

High-throughput

0.426

High

1010520

WRIP1
ATPase WRNIP1

1

0

High-throughput

0.426

High

877654

SL9A3
Sodium/hydrogen exchanger 3

1

2

High-throughput

0.407

High

1010479

SL9A4
Sodium/hydrogen exchanger 4

1

2

High-throughput

0.407

High

1010480

ZNT6
Zinc transporter 6

1

2

High-throughput

0.407

High

1010494

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

2

High-throughput

0.407

High

1010518

B3A4
Anion exchange protein 4

1

1

High-throughput

0.407

High

1010519

S26A8
Testis anion transporter 1

1

1

High-throughput

0.407

High

1010549

S27A5
Long-chain fatty acid transport protein 5

1

2

High-throughput

0.407

High

1010468

EREP1
Endosomal transmembrane epsin interactor 1

3

0

High-throughput

0.347

High

1010514

TSN17
Tetraspanin-17

3

0

High-throughput

0.347

High

1010535

TMM9B
Transmembrane protein 9B

3

0

High-throughput

0.345

High

1010474

MPPE1
Metallophosphoesterase 1

2

0

High-throughput

0.328

High

1010506

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

0

High-throughput

0.328

High

49779

CLRN2
Clarin-2

1

0

High-throughput

0.279

Low

248468

O10H2
Olfactory receptor 10H2

1

0

High-throughput

0.279

Low

261150

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.279

Low

560965

GP1BB
Platelet glycoprotein Ib beta chain

1

0

High-throughput

0.279

Low

771763

SCN4A
Sodium channel protein type 4 subunit alpha

1

0

High-throughput

0.279

Low

934458

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.279

Low

1010464

ABRX2
BRISC complex subunit Abraxas 2

1

0

High-throughput

0.279

Low

1010466

CIP4
Cdc42-interacting protein 4

1

0

High-throughput

0.279

Low

1010467

TRIP6
Thyroid receptor-interacting protein 6

1

0

High-throughput

0.279

Low

1010472

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

0

High-throughput

0.279

Low

1010475

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.279

Low

1010499

NPL4
Nuclear protein localization protein 4 homolog

1

0

High-throughput

0.279

Low

1010510

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

0

High-throughput

0.279

Low

1010512

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

1010515

ZDH12
Palmitoyltransferase ZDHHC12

1

0

High-throughput

0.279

Low

1010532

RABE2
Rab GTPase-binding effector protein 2

1

0

High-throughput

0.279

Low

1010534

KCMB3
Calcium-activated potassium channel subunit beta-3

1

0

High-throughput

0.279

Low

1010538

BABA1
BRISC and BRCA1-A complex member 1

1

0

High-throughput

0.279

Low

1010539

BABA2
BRISC and BRCA1-A complex member 2

1

0

High-throughput

0.279

Low

1010541

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.279

Low

1010545

RABX5
Rab5 GDP/GTP exchange factor

1

0

High-throughput

0.279

Low

464146

TPM2
Tropomyosin beta chain

1

0

High-throughput

0.249

Low

568053

HLAE
HLA class I histocompatibility antigen, alpha chain E

1

0

High-throughput

0.249

Low

906869

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.249

Low

999338

HBB
Hemoglobin subunit beta

1

0

High-throughput

0.249

Low

1010463

SCRIB
Protein scribble homolog

1

0

Small-scale

0.249

Low

1010503

SETD7
Histone-lysine N-methyltransferase SETD7

1

0

High-throughput

0.249

Low

1010528

CFA74
Cilia- and flagella-associated protein 74

1

0

High-throughput

0.249

Low

517287

ZTRF1
Zinc finger TRAF-type-containing protein 1

1

0

High-throughput

0.232

Low

1010487

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

0

High-throughput

0.232

Low

1010496

MACOI
Macoilin

1

0

High-throughput

0.232

Low

1010526

GTR11
Solute carrier family 2, facilitated glucose transporter member 11

1

0

High-throughput

0.232

Low

1010529

TOLIP
Toll-interacting protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025