HitPredict

Interactor 1: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (EC 3.6.1.-) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36517590
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 746 Hs			1 543
+	Mm
		1009920 Q6AXH7_MOUSE (1-746): 0: 833: 96.41		TCPH_MOUSE (1-543): 0: 656: 95.96
+	Hs
		881941 EZH2_HUMAN (1-746): 0: 864: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		875976 EZH2_HUMAN (1-746): 0: 864: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		610678 EZH2_HUMAN (1-746): 0: 864: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Mm
		1009996 Q6AXH7_MOUSE (1-746): 0: 833: 96.41		TCPG_MOUSE (1-541): 0: 574: 30.91
+	Hs
		899400 EZH2_HUMAN (1-746): 0: 864: 100.00		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Mm
		1009952 Q6AXH7_MOUSE (1-746): 0: 833: 96.41		TCPD_MOUSE (24-520): 1.63e-90: 289: 34.38
+	Mm
		550724 Q6AXH7_MOUSE (1-746): 0: 833: 96.41		TCPA_MOUSE (14-528): 2.95e-88: 284: 35.20
+	Hs
		1396292 EHMT2_HUMAN (467-732): 1.85e-68: 247: 24.21		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		1407571 SUV92_HUMAN (447-734): 5.91e-74: 247: 24.10		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Sc
		805548 SET1_YEAST (205-733): 1.2e-84: 291: 16.01		TCPH_YEAST (2-542): 0: 587: 62.45
+	Sc
		805541 SET1_YEAST (205-733): 1.2e-84: 291: 16.01		TCPG_YEAST (2-527): 0: 546: 30.68
+	Hs
		882094 EHMT2_HUMAN (467-732): 1.85e-68: 247: 24.21		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		882161 SUV92_HUMAN (447-734): 5.91e-74: 247: 24.10		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		876170 SUV92_HUMAN (447-734): 5.91e-74: 247: 24.10		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		216390 SUV91_HUMAN (354-731): 2.69e-71: 240: 19.90		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		610831 EHMT2_HUMAN (467-732): 1.85e-68: 247: 24.21		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		610891 SUV92_HUMAN (447-734): 5.91e-74: 247: 24.10		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		216374 SUV91_HUMAN (354-731): 2.69e-71: 240: 19.90		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		899582 SUV92_HUMAN (447-734): 5.91e-74: 247: 24.10		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79