HitPredict

Interactor 1: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Interactor 2: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30196744
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CAF1C_H4-bd~WD40, WD40~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 607
+	Hs
		1227562 NLE1_HUMAN (202-424): 2.44e-45: 165: 20.71		A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00
+	Hs
		845316 LIS1_HUMAN (6-207): 8.16e-43: 156: 11.45		A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00
+	Hs
		1066349 RBBP4_HUMAN (1-209): 1.71e-39: 148: 12.72		A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00
+	Hs
		1149777 TAF5_HUMAN (7-255): 5.95e-37: 145: 17.32		A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00
+	Mm
		1222099 RBBP7_MOUSE (1-425): 1.27e-117: 351: 99.77		A16L1_MOUSE (436-605): 1.39e-26: 116: 15.25
+	Hs
		965276 NLE1_HUMAN (202-424): 2.44e-45: 165: 20.71		WDR5_HUMAN (177-474): 3.11e-58: 200: 17.43
+	Hs
		984306 NLE1_HUMAN (202-424): 2.44e-45: 165: 20.71		GBB2_HUMAN (164-516): 1.54e-55: 193: 16.30
+	Dm
		1463899 WDS_DROME (212-422): 1.16e-43: 158: 19.91		WDS_DROME (210-478): 2.84e-57: 198: 18.12
+	Hs
		845264 LIS1_HUMAN (6-207): 8.16e-43: 156: 11.45		WDR5_HUMAN (177-474): 3.11e-58: 200: 17.43
+	Hs
		965071 WDR5B_HUMAN (218-422): 9.09e-42: 152: 21.46		WDR5_HUMAN (177-474): 3.11e-58: 200: 17.43
+	Hs
		964891 RBBP4_HUMAN (1-209): 1.71e-39: 148: 12.72		WDR5_HUMAN (177-474): 3.11e-58: 200: 17.43
+	Hs
		845250 LIS1_HUMAN (6-207): 8.16e-43: 156: 11.45		LIS1_HUMAN (99-438): 4.66e-48: 175: 14.72
+	Mm
		988931 LIS1_MOUSE (6-207): 6.24e-43: 157: 11.45		LIS1_MOUSE (99-438): 1.04e-47: 174: 14.72
+	Hs
		1450936 NLE1_HUMAN (202-424): 2.44e-45: 165: 20.71		NLE1_HUMAN (441-607): 8.65e-43: 162: 20.34
+	Mm
		1297665 TAF5_MOUSE (152-424): 2.6e-46: 172: 15.77		A16L1_MOUSE (436-605): 1.39e-26: 116: 15.25
+	Mm
		983625 RACK1_MOUSE (213-405): 5.45e-28: 114: 20.41		GBB1_MOUSE (165-516): 2.35e-43: 160: 17.18
+	Mm
		1222074 RBBP4_MOUSE (1-209): 1.71e-39: 148: 12.72		A16L1_MOUSE (436-605): 1.39e-26: 116: 15.25
+	Hs
		1334151 POC1B_HUMAN (2-170): 1.09e-35: 138: 9.77		POC1A_HUMAN (482-607): 3.81e-29: 121: 23.02
+	Hs
		323047 POC1B_HUMAN (2-170): 1.09e-35: 138: 9.77		WDR47_HUMAN (315-396): 9.66e-11: 67: 22.62