Interactor 1: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8

Interactor 2: LSM2 (Q9Y333)
U6 snRNA-associated Sm-like protein LSm2 (Protein G7b) (Small nuclear ribonuclear protein D homolog) (snRNP core Sm-like protein Sm-x5)
Gene: LSM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 28515276, 29395067
Identification Methods affinity chromatography technology, proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LSM~PRP8_domainIV
Common GO terms GO:0000244 - spliceosomal tri-snRNP complex assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 4 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 2335
Hs

1 95
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024