HitPredict

Interactor 1: DREB (Q16643)
Drebrin (Developmentally-regulated brain protein)
Gene: DBN1

Interactor 2: ACTBL (Q562R1)
Beta-actin-like protein 2 (Kappa-actin)
Gene: ACTBL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.855

Property	Details
Experiments	28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Cofilin_ADF
Common GO terms	GO:0005737 - cytoplasm GO:0015629 - actin cytoskeleton GO:0098978 - glutamatergic synapse
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 649 Hs			1 376
+	Hs
		952855 DREB_HUMAN (1-649): 3.27e-95: 308: 100.00		ACTB_HUMAN (3-376): 0: 595: 91.71
+	Hs
		993194 DREB_HUMAN (1-649): 3.27e-95: 308: 100.00		ACTG_HUMAN (3-376): 0: 594: 91.44
+	Hs
		995623 DREB_HUMAN (1-649): 3.27e-95: 308: 100.00		ACTC_HUMAN (2-376): 0: 589: 88.27
+	Hs
		977706 DREB_HUMAN (1-649): 3.27e-95: 308: 100.00		ACTA_HUMAN (1-376): 0: 586: 87.80
+	Hs
		953170 DBNL_HUMAN (3-464): 9.9e-75: 248: 29.98		ACTB_HUMAN (3-376): 0: 595: 91.71
+	Hs
		995882 DBNL_HUMAN (3-464): 9.9e-75: 248: 29.98		ACTC_HUMAN (2-376): 0: 589: 88.27
+	Ce
		534399 Q9XUT0_CAEEL (4-619): 3.41e-47: 178: 16.46		ACT2_CAEEL (1-376): 0: 599: 90.16
+	Hs
		952994 CTTB2_HUMAN (131-627): 2.71e-32: 136: 14.70		ACTB_HUMAN (3-376): 0: 595: 91.71
+	Hs
		215916 SYNJ1_HUMAN (126-645): 3.15e-29: 126: 9.77		ACTC_HUMAN (2-376): 0: 589: 88.27
+	Dm
		1014444 TITIN_DROME (173-542): 3.1e-27: 120: 13.80		ACT6_DROME (1-376): 0: 594: 88.83
+	Sc
		587330 ABP1_YEAST (4-512): 1.46e-30: 128: 13.41		ACT_YEAST (1-376): 0: 583: 82.98
+	Dm
		1014448 Q9VDF4_DROME (152-461): 2.5e-18: 91: 14.82		ACT6_DROME (1-376): 0: 594: 88.83
+	Dm
		56405 A1ZA72_DROME (119-643): 3.13e-17: 88.7: 8.97		ACT6_DROME (1-376): 0: 594: 88.83