Protein: DBNL
Drebrin-like protein (Cervical SH3P7) (Cervical mucin-associated protein) (Drebrin-F) (HPK1-interacting protein of 55 kDa) (HIP-55) (SH3 domain-containing protein 7)

Gene: DBNL
Organism: Homo sapiens
Interactions: 141
UniProt ID: Q9UJU6

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001726 - ruffle
GO:0002102 - podosome
GO:0002250 - adaptive immune response
GO:0003779 - actin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

849084

ZAP70
Tyrosine-protein kinase ZAP-70

1

20

Small-scale

0.747

High

1435572

SH24A
SH2 domain-containing protein 4A

5

20

High-throughput

0.728

High

343100

HERC2
E3 ubiquitin-protein ligase HERC2

5

11

High-throughput

0.714

High

1417984

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

20

High-throughput

0.698

High

1256809

FGD6
FYVE, RhoGEF and PH domain-containing protein 6

4

19

High-throughput

0.694

High

51619

SPD2B
SH3 and PX domain-containing protein 2B

1

19

High-throughput

0.691

High

867499

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.691

High

284627

ECI2
Enoyl-CoA delta isomerase 2

3

2

High-throughput

0.667

High

1287702

RBM23
Probable RNA-binding protein 23

3

6

High-throughput

0.667

High

1460650

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

3

11

High-throughput

0.667

High

650476

FGFR3
Fibroblast growth factor receptor 3

1

20

High-throughput

0.665

High

856975

BAG6
Large proline-rich protein BAG6

1

20

High-throughput

0.665

High

1460648

UBQL1
Ubiquilin-1

1

9

High-throughput

0.665

High

1339568

NEUA
N-acylneuraminate cytidylyltransferase

3

0

High-throughput

0.638

High

709026

T2EB
Transcription initiation factor IIE subunit beta

2

1

High-throughput

0.628

High

1004317

3BP2
SH3 domain-binding protein 2

3

19

Small-scale

0.623

High

412775

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

953170

ACTB
Actin, cytoplasmic 1

1

20

High-throughput

0.618

High

958217

ARP3
Actin-related protein 3

1

20

High-throughput

0.618

High

995882

ACTC
Actin, alpha cardiac muscle 1

1

20

High-throughput

0.618

High

1460645

DBNL
Drebrin-like protein

1

15

High-throughput

0.618

High

538080

HSP7C
Heat shock cognate 71 kDa protein

2

8

High-throughput

0.601

High

564530

CFTR
Cystic fibrosis transmembrane conductance regulator

2

6

High-throughput

0.601

High

1367892

ARC1A
Actin-related protein 2/3 complex subunit 1A

2

10

High-throughput

0.601

High

791818

SYUA
Alpha-synuclein

2

5

Small-scale

0.584

High

831613

CCNF
Cyclin-F

2

4

High-throughput

0.584

High

1164618

MIC60
MICOS complex subunit MIC60

2

1

High-throughput

0.584

High

397174

ESR1
Estrogen receptor

2

16

High-throughput

0.571

High

1253244

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

2

19

High-throughput

0.571

High

1370671

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

16

Small-scale

0.561

High

928582

TERF1
Telomeric repeat-binding factor 1

1

7

High-throughput

0.552

High

1452465

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

3

High-throughput

0.552

High

179412

ARPC2
Actin-related protein 2/3 complex subunit 2

1

3

High-throughput

0.536

High

192758

ARPC5
Actin-related protein 2/3 complex subunit 5

1

5

High-throughput

0.536

High

210797

KLK10
Kallikrein-10

1

3

High-throughput

0.536

High

387915

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

4

High-throughput

0.536

High

602849

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.536

High

612006

RL35A
Large ribosomal subunit protein eL33

1

4

High-throughput

0.536

High

652435

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

2

High-throughput

0.536

High

733463

CCR1
C-C chemokine receptor type 1

1

8

High-throughput

0.536

High

866859

CAZA2
F-actin-capping protein subunit alpha-2

1

6

High-throughput

0.536

High

926694

HIRA
Protein HIRA

1

6

High-throughput

0.536

High

931153

HSP72
Heat shock-related 70 kDa protein 2

1

8

High-throughput

0.536

High

966996

1433G
14-3-3 protein gamma

1

15

High-throughput

0.536

High

1049890

1433F
14-3-3 protein eta

1

15

High-throughput

0.536

High

1052122

CALD1
Caldesmon

1

20

High-throughput

0.536

High

1110588

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

6

High-throughput

0.536

High

1186327

MA7D1
MAP7 domain-containing protein 1

1

9

High-throughput

0.536

High

1409700

ARP5L
Actin-related protein 2/3 complex subunit 5-like protein

1

5

High-throughput

0.536

High

1417093

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

13

High-throughput

0.536

High

1454584

KLH14
Kelch-like protein 14

1

6

High-throughput

0.536

High

1460654

SAR1B
Small COPII coat GTPase SAR1B

1

3

High-throughput

0.536

High

1383382

ACD
Adrenocortical dysplasia protein homolog

1

3

High-throughput

0.523

High

549259

CDK4
Cyclin-dependent kinase 4

1

3

High-throughput

0.515

High

607826

ATTY
Tyrosine aminotransferase

1

2

High-throughput

0.515

High

624171

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

12

High-throughput

0.515

High

1352009

RBCC1
RB1-inducible coiled-coil protein 1

1

20

High-throughput

0.515

High

1460649

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

6

High-throughput

0.515

High

167417

KLF11
Krueppel-like factor 11

1

6

High-throughput

0.515

High

442518

GELS
Gelsolin

1

7

High-throughput

0.515

High

844071

HD
Huntingtin

1

9

High-throughput

0.515

High

1133930

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

15

High-throughput

0.515

High

347398

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

483658

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

0

High-throughput

0.513

High

1247775

PAQR3
Progestin and adipoQ receptor family member 3

1

0

High-throughput

0.513

High

1408253

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.513

High

1446324

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.513

High

1460646

TM11E
Transmembrane protease serine 11E

1

0

High-throughput

0.513

High

1460651

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.513

High

1460655

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.513

High

1450183

POTE1
Protection of telomeres protein 1

1

4

High-throughput

0.504

High

161103

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

20

Small-scale

0.501

High

186107

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

840095

CASP3
Caspase-3

1

2

Small-scale

0.501

High

1295226

HOME1
Homer protein homolog 1

1

20

Small-scale

0.501

High

1460647

DNPEP
Aspartyl aminopeptidase

1

0

High-throughput

0.493

High

160020

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.493

High

177479

ZN536
Zinc finger protein 536

1

1

High-throughput

0.489

High

1256489

UBN2
Ubinuclein-2

1

20

High-throughput

0.489

High

1460605

ZF69B
Zinc finger protein 69 homolog B

1

2

High-throughput

0.489

High

210615

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

1

3

High-throughput

0.479

High

346466

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

8

High-throughput

0.479

High

347986

BAG3
BAG family molecular chaperone regulator 3

1

2

High-throughput

0.479

High

376074

RASK
GTPase KRas

1

20

High-throughput

0.479

High

530541

TAU
Microtubule-associated protein tau

1

20

High-throughput

0.479

High

556407

CADH1
Cadherin-1

1

7

High-throughput

0.479

High

599229

IL7RA
Interleukin-7 receptor subunit alpha

1

1

High-throughput

0.479

High

607201

CEBPB
CCAAT/enhancer-binding protein beta

1

4

High-throughput

0.479

High

651455

CBL
E3 ubiquitin-protein ligase CBL

1

20

Small-scale

0.479

High

862532

YAP1
Transcriptional coactivator YAP1

1

18

High-throughput

0.479

High

1085638

FOXO1
Forkhead box protein O1

1

5

High-throughput

0.479

High

1094652

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

6

High-throughput

0.479

High

1098213

DUS8
Dual specificity protein phosphatase 8

1

6

High-throughput

0.479

High

1107316

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

1112772

CUL1
Cullin-1

1

5

High-throughput

0.479

High

1116107

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

8

High-throughput

0.479

High

1135844

HAPR1
HUWE1-associated protein modifying stress responses 1

1

1

High-throughput

0.479

High

1153753

TOM34
Mitochondrial import receptor subunit TOM34

1

7

High-throughput

0.479

High

1227666

A16L1
Autophagy-related protein 16-1

1

17

High-throughput

0.479

High

1256014

TRI67
Tripartite motif-containing protein 67

1

18

High-throughput

0.479

High

1289699

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.479

High

1308754

M4K3
Mitogen-activated protein kinase kinase kinase kinase 3

1

15

High-throughput

0.479

High

1339022

NUP43
Nucleoporin Nup43

1

8

High-throughput

0.479

High

1350494

BICD2
Protein bicaudal D homolog 2

1

20

High-throughput

0.479

High

1363888

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

4

High-throughput

0.479

High

1364297

TOPB1
DNA topoisomerase 2-binding protein 1

1

7

High-throughput

0.479

High

1364664

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

8

High-throughput

0.479

High

1367536

ESR2
Estrogen receptor beta

1

16

High-throughput

0.479

High

1368667

KAT6A
Histone acetyltransferase KAT6A

1

5

Small-scale

0.479

High

1391207

BICD1
Protein bicaudal D homolog 1

1

20

High-throughput

0.479

High

1400349

FMNL2
Formin-like protein 2

1

3

High-throughput

0.479

High

1429006

WWTR1
WW domain-containing transcription regulator protein 1

1

17

High-throughput

0.479

High

1434180

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1435423

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

1449616

SEM4G
Semaphorin-4G

1

1

High-throughput

0.479

High

1459237

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

1459527

TES
Testin

1

8

High-throughput

0.479

High

1459579

KDM5B
Lysine-specific demethylase 5B

1

1

Small-scale

0.479

High

1460652

M4K5
Mitogen-activated protein kinase kinase kinase kinase 5

1

19

High-throughput

0.479

High

1460653

TRI17
E3 ubiquitin-protein ligase TRIM17

1

9

Small-scale

0.479

High

1460656

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

3

High-throughput

0.479

High

1023323

CP4F8
Cytochrome P450 4F8

1

1

High-throughput

0.470

High

1098607

GPS2
G protein pathway suppressor 2

1

0

High-throughput

0.458

High

1429877

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

788338

GPX4
Phospholipid hydroperoxide glutathione peroxidase GPX4

1

2

High-throughput

0.445

High

1449912

DDX28
Probable ATP-dependent RNA helicase DDX28

1

5

High-throughput

0.445

High

106821

APRIO
Alternative prion protein

1

8

High-throughput

0.437

High

373441

MYC
Myc proto-oncogene protein

1

9

High-throughput

0.437

High

589984

RFA2
Replication protein A 32 kDa subunit

1

10

High-throughput

0.437

High

696809

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

769463

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.437

High

1096855

RFA4
Replication protein A 30 kDa subunit

1

10

High-throughput

0.437

High

1155885

EZH2
Histone-lysine N-methyltransferase EZH2

1

7

High-throughput

0.437

High

1400942

VPS35
Vacuolar protein sorting-associated protein 35

1

0

Small-scale

0.426

High

1395421

NEUL4
Neuralized-like protein 4

6

0

High-throughput

0.379

High

1181355

CR021
UPF0711 protein C18orf21

1

0

High-throughput

0.279

Low

1326696

MESH1
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1

1

0

High-throughput

0.279

Low

1366724

ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

1

0

High-throughput

0.279

Low

1453405

HPBP1
Hsp70-binding protein 1

1

0

High-throughput

0.279

Low

1413000

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025