HitPredict

Interactor 1: H2A2C (Q16777)
Histone H2A type 2-C (H2A-clustered histone 20) (Histone H2A-GL101) (Histone H2A/q)
Gene: H2AC20

Interactor 2: MYSM1 (Q5VVJ2)
Deubiquitinase MYSM1 (2A-DUB) (EC 3.4.19.-) (Myb-like, SWIRM and MPN domain-containing protein 1)
Gene: MYSM1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	21245042, 17707232
Identification Methods	enzymatic study, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, deubiquitination reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 129 Hs			1 828
+	Hs
		419028 H2A1B_HUMAN (1-127): 8.33e-65: 194: 94.49		MYSM1_HUMAN (1-828): 0: 1085: 100.00
+	Hs
		591683 H2AX_HUMAN (1-123): 7.41e-64: 192: 95.12		MYSM1_HUMAN (1-828): 0: 1085: 100.00
+	Mm
		1229947 H2A2A_MOUSE (1-127): 3.39e-65: 195: 97.64		MYSM1_MOUSE (1-828): 0: 1025: 78.92
+	Hs
		1232701 H2A2A_HUMAN (1-127): 3.39e-65: 195: 97.64		SMRC2_HUMAN (177-520): 4.82e-100: 338: 17.75
+	Hs
		591747 H2AX_HUMAN (1-123): 7.41e-64: 192: 95.12		SMRC2_HUMAN (177-520): 4.82e-100: 338: 17.75
+	Hs
		591764 H2AX_HUMAN (1-123): 7.41e-64: 192: 95.12		SMRC1_HUMAN (186-520): 2.83e-92: 315: 17.97
+	Sc
		419390 H2A1_YEAST (16-129): 1.57e-52: 163: 78.95		SWI3_YEAST (187-542): 9.29e-63: 228: 16.94
+	Sc
		419660 H2A2_YEAST (16-129): 1.64e-52: 163: 78.95		SWI3_YEAST (187-542): 9.29e-63: 228: 16.94
+	Sc
		419783 H2A2_YEAST (16-129): 1.64e-52: 163: 78.95		RSC8_YEAST (286-572): 3.98e-53: 195: 15.18
+	Hs
		591881 H2AX_HUMAN (1-123): 7.41e-64: 192: 95.12		RCOR1_HUMAN (89-212): 3.16e-25: 112: 20.47
+	Hs
		246389 H2A1B_HUMAN (1-127): 8.33e-65: 194: 94.49		KDM1A_HUMAN (226-497): 1.17e-19: 96.5: 14.58