HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: LURA1 (Q96LR2)
Leucine rich adaptor protein 1 (Leucine repeat adapter protein 35A)
Gene: LURAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	25416956, 31515488
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 239
+	Hs
		1132667 FKB15_HUMAN (1-284): 5.16e-27: 112: 13.40		LURA1_HUMAN (1-239): 1.31e-151: 422: 100.00
+	Rn
		88958 MRCKB_RAT (3-285): 1.56e-12: 69.5: 14.09		LURA1_RAT (1-239): 4.58e-154: 429: 85.36
+	Hs
		1150630 MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65		LURA1_HUMAN (1-239): 1.31e-151: 422: 100.00
+	Hs
		1297344 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		LURA1_HUMAN (1-239): 1.31e-151: 422: 100.00
+	Hs
		1150621 MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65		LUR1L_HUMAN (49-158): 6.66e-36: 128: 42.37
+	Hs
		1217032 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		LUR1L_HUMAN (49-158): 6.66e-36: 128: 42.37