HitPredict

Interactor 1: CORO6 (Q6QEF8)
Coronin-6 (Coronin-like protein E) (Clipin-E)
Gene: CORO6

Interactor 2: TARA (Q9H2D6)
TRIO and F-actin-binding protein (Protein Tara) (TRF1-associated protein of 68 kDa) (Trio-associated repeat on actin)
Gene: TRIOBP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~WD40
Common GO terms	GO:0051015 - actin filament binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 472 Hs			1 2365
+	Hs
		724988 COR1B_HUMAN (1-470): 2.03e-114: 347: 67.15		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Mm
		292618 COR1A_MOUSE (1-463): 8.64e-110: 334: 67.46		PLEC_MOUSE (1808-2360): 6.57e-18: 93.9: 15.01
+	Hs
		724947 COR2A_HUMAN (1-472): 8.75e-94: 295: 43.75		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		965175 COR2B_HUMAN (1-471): 4.45e-90: 284: 43.42		ANK2_HUMAN (28-1012): 2.01e-09: 65.7: 14.82
+	Hs
		551882 WSB1_HUMAN (49-324): 1.36e-62: 211: 23.21		DESP_HUMAN (1531-2365): 6.57e-16: 86.9: 10.21
+	Hs
		903240 WDR5_HUMAN (2-249): 2.05e-59: 200: 13.55		PLEC_HUMAN (1579-2357): 3.47e-16: 88.1: 12.43
+	Hs
		551655 WDR5_HUMAN (2-249): 2.05e-59: 200: 13.55		DESP_HUMAN (1531-2365): 6.57e-16: 86.9: 10.21
+	Hs
		903334 WDR5_HUMAN (2-249): 2.05e-59: 200: 13.55		MYH14_HUMAN (2035-2363): 1.9e-15: 85.4: 15.06
+	Hs
		903374 WDR5_HUMAN (2-249): 2.05e-59: 200: 13.55		KMT2C_HUMAN (37-951): 1.09e-09: 66.5: 15.53
+	Mm
		903669 WDR5_MOUSE (2-249): 2.05e-59: 200: 13.55		KMT2C_MOUSE (57-845): 1.25e-09: 66.5: 16.45
+	Hs
		551766 WDR5B_HUMAN (164-383): 4.22e-46: 164: 14.55		DESP_HUMAN (1531-2365): 6.57e-16: 86.9: 10.21
+	Hs
		551632 LIS1_HUMAN (171-414): 5.36e-42: 155: 11.89		DESP_HUMAN (1531-2365): 6.57e-16: 86.9: 10.21
+	Hs
		725066 COR1C_HUMAN (2-209): 5.03e-19: 91.5: 13.06		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		728492 POC1A_HUMAN (255-413): 4.63e-18: 88: 6.86		MYH11_HUMAN (1483-2225): 1.16e-25: 119: 10.65
+	Hs
		551854 NLE1_HUMAN (2-109): 2.01e-22: 101: 15.74		DESP_HUMAN (1531-2365): 6.57e-16: 86.9: 10.21
+	Hs
		1056932 SNR40_HUMAN (251-377): 3.53e-17: 84.6: 6.30		MDC1_HUMAN (88-903): 1.81e-15: 85.4: 14.49
+	Hs
		551682 RBBP4_HUMAN (66-219): 1.8e-12: 70.9: 27.10		DESP_HUMAN (1531-2365): 6.57e-16: 86.9: 10.21