HitPredict

Interactor 1: DDR2 (Q16832)
Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)
Gene: DDR2

Interactor 2: LRC52 (Q8N7C0)
Leucine-rich repeat-containing protein 52 (BK channel auxiliary gamma subunit LRRC52)
Gene: LRRC52

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	LRR_8~PK_Tyr_Ser-Thr
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 855 Hs			1 313
+	Hs
		1063023 DDR1_HUMAN (22-853): 0: 654: 51.74		FLRT1_HUMAN (4-234): 8.7e-45: 163: 21.85
+	At
		1246802 SRF4_ARATH (198-852): 3.08e-149: 456: 14.35		BAME2_ARATH (75-307): 6.47e-30: 121: 16.53
+	At
		1192441 SRF5_ARATH (194-852): 1.49e-131: 411: 13.11		ERECT_ARATH (1-275): 7.52e-39: 147: 16.13
+	At
		88669 SRF5_ARATH (194-852): 1.49e-131: 411: 13.11		GSO1_ARATH (1-271): 1.17e-38: 147: 14.49
+	At
		1246785 SRF5_ARATH (194-852): 1.49e-131: 411: 13.11		ERL2_ARATH (1-296): 1.89e-37: 143: 15.67
+	At
		99913 F4I065_ARATH (347-851): 5.81e-123: 394: 19.85		MIK2_ARATH (36-306): 1.89e-40: 152: 16.25
+	At
		88668 SRF8_ARATH (190-852): 1.29e-122: 387: 13.27		GSO1_ARATH (1-271): 1.17e-38: 147: 14.49
+	At
		1246741 SRF8_ARATH (190-852): 1.29e-122: 387: 13.27		ERL2_ARATH (1-296): 1.89e-37: 143: 15.67
+	At
		235417 BIK1_ARATH (545-854): 1.44e-125: 385: 20.19		PEPR1_ARATH (1-311): 5.67e-38: 145: 15.21
+	At
		235416 BIK1_ARATH (545-854): 1.44e-125: 385: 20.19		FLS2_ARATH (5-313): 1.88e-36: 140: 15.87
+	At
		1246760 SRF8_ARATH (190-852): 1.29e-122: 387: 13.27		PXL1_ARATH (1-284): 7.65e-33: 130: 15.11
+	At
		88930 F4I065_ARATH (347-851): 5.81e-123: 394: 19.85		Y4361_ARATH (24-313): 1.94e-30: 123: 14.10
+	At
		89303 F4I065_ARATH (347-851): 5.81e-123: 394: 19.85		RGI2_ARATH (21-313): 2.39e-30: 123: 15.83
+	At
		99904 F4I065_ARATH (347-851): 5.81e-123: 394: 19.85		RGI4_ARATH (14-313): 3.51e-30: 122: 16.09
+	At
		99918 F4I065_ARATH (347-851): 5.81e-123: 394: 19.85		TDR_ARATH (1-219): 5.68e-30: 121: 13.90
+	At
		99930 F4I065_ARATH (347-851): 5.81e-123: 394: 19.85		BAME2_ARATH (75-307): 6.47e-30: 121: 16.53
+	At
		1246757 SRF8_ARATH (190-852): 1.29e-122: 387: 13.27		TDR_ARATH (1-219): 5.68e-30: 121: 13.90
+	Hs
		541724 FGFR1_HUMAN (505-851): 3.16e-102: 337: 32.49		FLRT1_HUMAN (4-234): 8.7e-45: 163: 21.85
+	Mm
		591449 FGFR1_MOUSE (505-851): 3.19e-102: 337: 32.49		FLRT1_MOUSE (4-234): 8.44e-45: 163: 21.85
+	Hs
		412125 NTRK1_HUMAN (551-850): 4.93e-101: 333: 42.62		ISLR2_HUMAN (2-114): 2.15e-12: 69.5: 22.12