HitPredict

Interactor 1: UBC7 (O00102)
Ubiquitin-conjugating enzyme E2-18 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 7) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)
Gene: UBC7

Interactor 2: UBA1 (O94609)
Ubiquitin-activating enzyme E1 1 (EC 6.2.1.45) (Poly(A)+ RNA transport protein 3)
Gene: ptr3

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.799

Property	Details
Experiments	28162934, 31397327
Identification Methods	enzymatic study, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	E1_UFD~UQ_con, ThiF~UQ_con
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 166 Sp			1 1012
+	Hs
		607190 UB2D4_HUMAN (5-165): 1.06e-73: 219: 34.78		UBA1_HUMAN (1-1012): 0: 1212: 52.97
+	Hs
		607026 UB2D1_HUMAN (5-165): 9.48e-73: 217: 34.16		UBA1_HUMAN (1-1012): 0: 1212: 52.97
+	Hs
		607050 UB2D2_HUMAN (5-165): 1.6e-72: 216: 34.16		UBA1_HUMAN (1-1012): 0: 1212: 52.97
+	Oc
		1100193 UB2R2_RABIT (1-163): 4.35e-71: 215: 44.38		UBA1_RABIT (2-1012): 0: 1211: 53.12
+	Hs
		607039 UB2D3_HUMAN (5-165): 2.3e-71: 213: 33.54		UBA1_HUMAN (1-1012): 0: 1212: 52.97
+	Hs
		607046 UB2G1_HUMAN (1-163): 2.17e-70: 211: 49.39		UBA1_HUMAN (1-1012): 0: 1212: 52.97
+	Hs
		607038 UB2G2_HUMAN (1-166): 5.92e-69: 207: 66.87		UBA1_HUMAN (1-1012): 0: 1212: 52.97
+	Hs
		607136 UB2E2_HUMAN (4-164): 1.28e-66: 203: 27.95		UBA1_HUMAN (1-1012): 0: 1212: 52.97
+	Hs
		607129 UB2E3_HUMAN (4-164): 2.33e-66: 202: 28.57		UBA1_HUMAN (1-1012): 0: 1212: 52.97
+	Sp
		293848 UBC4_SCHPO (5-164): 3.6e-71: 212: 32.50		UBA1_SCHPO (1-1012): 0: 1193: 100.00
+	Sp
		293852 UBC15_SCHPO (1-152): 6.23e-50: 159: 51.32		UBA1_SCHPO (1-1012): 0: 1193: 100.00
+	Sc
		549788 UBC4_YEAST (1-164): 1.31e-71: 213: 29.88		UBA1_YEAST (2-1012): 0: 1122: 58.44
+	Sc
		608719 UBC7_YEAST (3-166): 1.07e-68: 207: 60.37		UBA1_YEAST (2-1012): 0: 1122: 58.44
+	Hs
		48104 UB2D1_HUMAN (5-165): 9.48e-73: 217: 34.16		UBA6_HUMAN (2-1012): 0: 1038: 39.69
+	Hs
		48107 UB2D2_HUMAN (5-165): 1.6e-72: 216: 34.16		UBA6_HUMAN (2-1012): 0: 1038: 39.69
+	Hs
		48106 UB2D3_HUMAN (5-165): 2.3e-71: 213: 33.54		UBA6_HUMAN (2-1012): 0: 1038: 39.69
+	Hs
		48105 UB2G2_HUMAN (1-166): 5.92e-69: 207: 66.87		UBA6_HUMAN (2-1012): 0: 1038: 39.69
+	Sc
		854609 UBC7_YEAST (3-166): 1.07e-68: 207: 60.37		UBA2_YEAST (409-1009): 1.22e-78: 271: 21.95
+	Hs
		1282360 UB2E3_HUMAN (4-164): 2.33e-66: 202: 28.57		SAE2_HUMAN (25-385): 5.42e-77: 267: 13.29
+	Hs
		919796 UB2D2_HUMAN (5-165): 1.6e-72: 216: 34.16		UBA3_HUMAN (794-973): 2.22e-40: 157: 19.47