HitPredict

Interactor 1: KDM1A (Q6ZQ88)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2)
Gene: KDM1A

Interactor 2: MCAF1 (Q7TT18)
Activating transcription factor 7-interacting protein 1 (ATFa-associated modulator) (mAM) (MBD1-containing chromatin-associated factor 1)
Gene: Atf7ip

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34709266
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 853 Mm			1 1306
+	Mm
		1112901 KDM1A_MOUSE (1-853): 0: 998: 100.00		MCAF2_MOUSE (1192-1296): 6.04e-26: 114: 51.43
+	Hs
		232022 KDM1A_HUMAN (1-853): 0: 1019: 98.12		NU214_HUMAN (13-1157): 1.67e-14: 81.4: 9.38
+	Hs
		203190 KDM1A_HUMAN (1-853): 0: 1019: 98.12		SYNJ1_HUMAN (595-1029): 2.56e-09: 64.3: 10.42
+	Hs
		231904 KDM1A_HUMAN (1-853): 0: 1019: 98.12		ANR17_HUMAN (733-1078): 3.25e-09: 63.9: 15.86
+	Hs
		1056891 KDM1B_HUMAN (124-496): 1.43e-82: 284: 23.53		MDC1_HUMAN (11-1268): 9.57e-34: 144: 9.78
+	Hs
		1239571 KDM1B_HUMAN (124-496): 1.43e-82: 284: 23.53		KMT2C_HUMAN (793-1225): 6.45e-11: 69.7: 14.45