HitPredict

Interactor 1: CKS1 (Q24152)
Cyclin-dependent kinases regulatory subunit
Gene: Cks30A

Interactor 2: CCNB3 (Q9I7I0)
G2/mitotic-specific cyclin-B3
Gene: CycB3

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0035186 - syncytial blastoderm mitotic cell cycle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 74 Dm			1 575
+	Dm
		1439951 Q9VHN1_DROME (2-72): 5.13e-38: 123: 64.79		CCNB3_DROME (1-575): 0: 595: 100.00
+	Dm
		632453 CKS1_DROME (1-74): 2.11e-38: 123: 100.00		CCNB_DROME (49-561): 9.64e-125: 378: 24.67
+	Dm
		632479 Q9VHN1_DROME (2-72): 5.13e-38: 123: 64.79		CCNB_DROME (49-561): 9.64e-125: 378: 24.67
+	At
		200127 CKS1_ARATH (4-71): 1.59e-36: 119: 67.65		CCB24_ARATH (114-556): 2.73e-119: 361: 23.27
+	At
		1456428 CKS2_ARATH (4-71): 2.83e-36: 118: 69.12		CCB24_ARATH (114-556): 2.73e-119: 361: 23.27
+	At
		200097 CKS1_ARATH (4-71): 1.59e-36: 119: 67.65		CCA23_ARATH (119-557): 3.21e-118: 359: 25.39
+	At
		200116 CKS1_ARATH (4-71): 1.59e-36: 119: 67.65		CCB23_ARATH (139-556): 1.78e-117: 356: 22.93
+	Hs
		325478 CKS1_HUMAN (3-71): 2.45e-35: 115: 78.26		CCNB2_HUMAN (170-569): 2.71e-117: 354: 25.62
+	At
		1426564 CKS2_ARATH (4-71): 2.83e-36: 118: 69.12		CCA31_ARATH (219-559): 7.25e-111: 337: 30.46
+	At
		200098 CKS1_ARATH (4-71): 1.59e-36: 119: 67.65		CCB12_ARATH (160-556): 4.26e-109: 335: 24.28
+	At
		1184295 CKS2_ARATH (4-71): 2.83e-36: 118: 69.12		CCB12_ARATH (160-556): 4.26e-109: 335: 24.28
+	At
		49217 CKS1_ARATH (4-71): 1.59e-36: 119: 67.65		CCA33_ARATH (259-556): 5.04e-109: 331: 31.60
+	At
		49245 CKS2_ARATH (4-71): 2.83e-36: 118: 69.12		CCA33_ARATH (259-556): 5.04e-109: 331: 31.60
+	At
		200100 CKS1_ARATH (4-71): 1.59e-36: 119: 67.65		CCA34_ARATH (219-559): 4.25e-105: 322: 29.35
+	At
		1185697 CKS2_ARATH (4-71): 2.83e-36: 118: 69.12		CCA34_ARATH (219-559): 4.25e-105: 322: 29.35
+	At
		200083 CKS1_ARATH (4-71): 1.59e-36: 119: 67.65		CCB14_ARATH (183-559): 1.15e-103: 319: 26.10
+	At
		200099 CKS1_ARATH (4-71): 1.59e-36: 119: 67.65		CCB22_ARATH (211-553): 4.22e-102: 317: 26.76
+	At
		1184316 CKS2_ARATH (4-71): 2.83e-36: 118: 69.12		CCB22_ARATH (211-553): 4.22e-102: 317: 26.76
+	Dm
		575843 CKS1_DROME (1-74): 2.11e-38: 123: 100.00		CCNA_DROME (148-556): 6.88e-99: 311: 25.12
+	Dm
		575864 Q9VHN1_DROME (2-72): 5.13e-38: 123: 64.79		CCNA_DROME (148-556): 6.88e-99: 311: 25.12