HitPredict

Interactor 1: CCNB (P20439)
G2/mitotic-specific cyclin-B
Gene: CycB

Interactor 2: Q9VHN1 (Q9VHN1)
Cyclin-dependent kinases regulatory subunit
Gene: Cks85A

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 530 Dm			1 96
+	Dm
		632453 CCNB_DROME (1-530): 5.35e-179: 515: 100.00		CKS1_DROME (3-73): 1.95e-39: 127: 64.79
+	Dm
		1439951 CCNB3_DROME (28-516): 2.71e-109: 339: 23.17		Q9VHN1_DROME (1-96): 1.43e-58: 176: 100.00
+	At
		200127 CCB24_ARATH (86-520): 5.26e-123: 369: 26.08		CKS1_ARATH (5-72): 6.83e-39: 126: 72.06
+	At
		1456428 CCB24_ARATH (86-520): 5.26e-123: 369: 26.08		CKS2_ARATH (5-72): 1.45e-37: 122: 67.65
+	At
		200116 CCB23_ARATH (87-519): 9.42e-120: 361: 27.46		CKS1_ARATH (5-72): 6.83e-39: 126: 72.06
+	Hs
		956644 CCNA1_HUMAN (109-521): 5.23e-116: 352: 23.89		CKS1_HUMAN (1-72): 3.81e-40: 129: 70.83
+	Hs
		753912 CCNA1_HUMAN (109-521): 5.23e-116: 352: 23.89		CKS2_HUMAN (1-72): 1.11e-38: 125: 68.06
+	Hs
		573785 CCNB1_HUMAN (101-526): 5.01e-113: 343: 32.19		CKS1_HUMAN (1-72): 3.81e-40: 129: 70.83
+	At
		200098 CCB12_ARATH (73-519): 2.16e-113: 345: 28.11		CKS1_ARATH (5-72): 6.83e-39: 126: 72.06
+	Hs
		573763 CCNB1_HUMAN (101-526): 5.01e-113: 343: 32.19		CKS2_HUMAN (1-72): 1.11e-38: 125: 68.06
+	At
		1184295 CCB12_ARATH (73-519): 2.16e-113: 345: 28.11		CKS2_ARATH (5-72): 1.45e-37: 122: 67.65
+	Dm
		1172574 CCNB3_DROME (28-516): 2.71e-109: 339: 23.17		CKS1_DROME (3-73): 1.95e-39: 127: 64.79
+	At
		200097 CCA23_ARATH (54-518): 2.45e-109: 334: 25.11		CKS1_ARATH (5-72): 6.83e-39: 126: 72.06
+	Hs
		325478 CCNB2_HUMAN (148-523): 2.64e-108: 330: 34.13		CKS1_HUMAN (1-72): 3.81e-40: 129: 70.83
+	Hs
		325469 CCNB2_HUMAN (148-523): 2.64e-108: 330: 34.13		CKS2_HUMAN (1-72): 1.11e-38: 125: 68.06
+	Hs
		629093 CCNA2_HUMAN (94-518): 2.63e-103: 318: 23.69		CKS1_HUMAN (1-72): 3.81e-40: 129: 70.83
+	Sc
		633234 CG22_YEAST (59-523): 3.83e-107: 330: 23.42		CKS1_YEAST (4-72): 4.22e-34: 116: 50.00
+	At
		49217 CCA33_ARATH (204-520): 1.53e-104: 318: 29.85		CKS1_ARATH (5-72): 6.83e-39: 126: 72.06
+	Hs
		629071 CCNA2_HUMAN (94-518): 2.63e-103: 318: 23.69		CKS2_HUMAN (1-72): 1.11e-38: 125: 68.06
+	At
		1426564 CCA31_ARATH (150-518): 1.13e-104: 319: 28.53		CKS2_ARATH (5-72): 1.45e-37: 122: 67.65