HitPredict

Interactor 1: CCNB3 (Q9I7I0)
G2/mitotic-specific cyclin-B3
Gene: CycB3

Interactor 2: Q9VHN1 (Q9VHN1)
Cyclin-dependent kinases regulatory subunit
Gene: Cks85A

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000278 - mitotic cell cycle GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 575 Dm			1 96
+	Dm
		1172574 CCNB3_DROME (1-575): 0: 595: 100.00		CKS1_DROME (3-73): 1.95e-39: 127: 64.79
+	Dm
		632479 CCNB_DROME (49-561): 9.64e-125: 378: 24.67		Q9VHN1_DROME (1-96): 1.43e-58: 176: 100.00
+	Dm
		632453 CCNB_DROME (49-561): 9.64e-125: 378: 24.67		CKS1_DROME (3-73): 1.95e-39: 127: 64.79
+	Hs
		573785 CCNB1_HUMAN (158-567): 1.04e-118: 359: 25.99		CKS1_HUMAN (1-72): 3.81e-40: 129: 70.83
+	At
		200127 CCB24_ARATH (114-556): 2.73e-119: 361: 23.27		CKS1_ARATH (5-72): 6.83e-39: 126: 72.06
+	At
		200097 CCA23_ARATH (119-557): 3.21e-118: 359: 25.39		CKS1_ARATH (5-72): 6.83e-39: 126: 72.06
+	Hs
		573763 CCNB1_HUMAN (158-567): 1.04e-118: 359: 25.99		CKS2_HUMAN (1-72): 1.11e-38: 125: 68.06
+	At
		1456428 CCB24_ARATH (114-556): 2.73e-119: 361: 23.27		CKS2_ARATH (5-72): 1.45e-37: 122: 67.65
+	Hs
		325478 CCNB2_HUMAN (170-569): 2.71e-117: 354: 25.62		CKS1_HUMAN (1-72): 3.81e-40: 129: 70.83
+	At
		200116 CCB23_ARATH (139-556): 1.78e-117: 356: 22.93		CKS1_ARATH (5-72): 6.83e-39: 126: 72.06
+	Hs
		629093 CCNA2_HUMAN (120-562): 4.63e-116: 353: 24.83		CKS1_HUMAN (1-72): 3.81e-40: 129: 70.83
+	Hs
		325469 CCNB2_HUMAN (170-569): 2.71e-117: 354: 25.62		CKS2_HUMAN (1-72): 1.11e-38: 125: 68.06
+	Hs
		629071 CCNA2_HUMAN (120-562): 4.63e-116: 353: 24.83		CKS2_HUMAN (1-72): 1.11e-38: 125: 68.06
+	Hs
		956644 CCNA1_HUMAN (196-563): 1.87e-112: 344: 29.52		CKS1_HUMAN (1-72): 3.81e-40: 129: 70.83
+	Sc
		633234 CG22_YEAST (50-569): 9.89e-117: 356: 23.21		CKS1_YEAST (4-72): 4.22e-34: 116: 50.00
+	Hs
		753912 CCNA1_HUMAN (196-563): 1.87e-112: 344: 29.52		CKS2_HUMAN (1-72): 1.11e-38: 125: 68.06
+	At
		200098 CCB12_ARATH (160-556): 4.26e-109: 335: 24.28		CKS1_ARATH (5-72): 6.83e-39: 126: 72.06
+	At
		1426564 CCA31_ARATH (219-559): 7.25e-111: 337: 30.46		CKS2_ARATH (5-72): 1.45e-37: 122: 67.65
+	At
		1184295 CCB12_ARATH (160-556): 4.26e-109: 335: 24.28		CKS2_ARATH (5-72): 1.45e-37: 122: 67.65
+	At
		49217 CCA33_ARATH (259-556): 5.04e-109: 331: 31.60		CKS1_ARATH (5-72): 6.83e-39: 126: 72.06