HitPredict

Interactor 1: ATG2A (Q2TAZ0)
Autophagy-related protein 2 homolog A
Gene: ATG2A

Interactor 2: WIPI4 (Q9Y484)
WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) (WD repeat-containing protein 45)
Gene: WDR45

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.698

The method score is based on:

Property Details
Experiments 30185561, 20562859, 34368840, 31412244
Identification Methods pull down, x-ray crystallography, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000045 - autophagosome assembly
GO:0000407 - phagophore assembly site
GO:0000422 - autophagy of mitochondrion
GO:0000425 - pexophagy
GO:0032266 - phosphatidylinositol-3-phosphate binding
and 3 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1938
Hs

1 360
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025