Interactor 1: LRC8D (Q7L1W4)
Volume-regulated anion channel subunit LRRC8D (Leucine-rich repeat-containing protein 5) (Leucine-rich repeat-containing protein 8D) (HsLRRC8D)
Gene: LRRC8D

Interactor 2: LRC8D (Q7L1W4)
Volume-regulated anion channel subunit LRRC8D (Leucine-rich repeat-containing protein 5) (Leucine-rich repeat-containing protein 8D) (HsLRRC8D)
Gene: LRRC8D

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.40 1.00 0.638

The method score is based on:

Property Details
Experiments 32415200
Identification Methods 3D electron microscopy, molecular sieving
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~LRR_8, Pannexin_like~Pannexin_like
Common GO terms GO:0001678 - intracellular glucose homeostasis
GO:0005225 - volume-sensitive anion channel activity
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
and 7 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 858
Hs

1 858
+ Dm
+ At
+ At
+ Hs
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Hs
+ At
+ At
+ At

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Last updated: 15 Jul 2024