HitPredict

Interactor 1: ZCCHV (Q7Z2W4)
Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13) (Inactive Poly [ADP-ribose] polymerase 13) (PARP13) (Zinc finger CCCH domain-containing protein 2) (Zinc finger antiviral protein) (ZAP)
Gene: ZC3HAV1

Interactor 2: AURKB (Q96GD4)
Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)
Gene: AURKB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31586073, 23443559
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 902 Hs			1 344
+	Hs
		681917 ZCCHV_HUMAN (1-902): 0: 1277: 100.00		AKT1_HUMAN (3-343): 6.77e-137: 399: 28.53
+	Hs
		681918 PARPT_HUMAN (273-895): 0: 578: 23.82		AKT1_HUMAN (3-343): 6.77e-137: 399: 28.53
+	Hs
		568716 PARPT_HUMAN (273-895): 0: 578: 23.82		KAPCA_HUMAN (36-342): 1.66e-134: 388: 26.18
+	Hs
		160640 PARPT_HUMAN (273-895): 0: 578: 23.82		AURKA_HUMAN (1-334): 2.45e-133: 387: 58.89
+	Mm
		250436 Q921K2_MOUSE (359-885): 2.87e-150: 471: 12.70		AURKB_MOUSE (1-340): 4.11e-136: 392: 83.19
+	Hs
		455757 PARP1_HUMAN (359-885): 5.92e-142: 449: 13.20		AURKB_HUMAN (1-344): 5.7e-136: 391: 100.00
+	Hs
		160604 PAR10_HUMAN (694-895): 4.97e-50: 193: 23.32		AURKA_HUMAN (1-334): 2.45e-133: 387: 58.89