HitPredict

Interactor 1: HFA1 (P32874)
Acetyl-CoA carboxylase, mitochondrial (ACC) (EC 6.4.1.2) [Includes: Biotin carboxylase (EC 6.3.4.14)]
Gene: HFA1

Interactor 2: ACAC (Q00955)
Acetyl-CoA carboxylase (ACC) (EC 6.4.1.2) (Fatty acid synthetase 3) (mRNA transport-defective protein 7) [Includes: Biotin carboxylase (EC 6.3.4.14)]
Gene: ACC1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 16554755
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ACC_central~ACC_central, ACCA_BT~ACC_central, ACC_central~Biotin_carb_N, ACC_central~Biotin_lipoyl, ACC_central~Carboxyl_trans, ACCA_BT~Biotin_carb_C, ACCA_BT~Biotin_carb_N, ACCA_BT~Carboxyl_trans, Biotin_carb_C~Biotin_carb_C, Biotin_carb_C~Biotin_carb_N, Biotin_carb_C~Biotin_lipoyl, Biotin_carb_C~Carboxyl_trans, Biotin_carb_C~CPSase_L_D2, Biotin_carb_N~Biotin_carb_N, Biotin_carb_N~Biotin_lipoyl, Biotin_carb_N~CPSase_L_D2, Biotin_lipoyl~Biotin_lipoyl, Biotin_lipoyl~Carboxyl_trans, Biotin_lipoyl~CPSase_L_D2, Carboxyl_trans~Carboxyl_trans and 1 others

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Common GO terms GO:0003989 - acetyl-CoA carboxylase activity
GO:0004075 - biotin carboxylase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0006633 - fatty acid biosynthetic process
and 3 others

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Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 2273
Sc

1 2233
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Mm
+ Mm
+ Sc
+ Pa
+ Ec
+ Hs
+ Hs

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Last updated: 11Aug2025