HitPredict

Interactor 1: SYTL5 (Q80T23)
Synaptotagmin-like protein 5
Gene: SYTL5

Interactor 2: RB27A (Q9ERI2)
Ras-related protein Rab-27A (EC 3.6.5.2)
Gene: Rab27a

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	12051743
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FYVE_2~Ras
Common GO terms	GO:0006887 - exocytosis GO:0070382 - exocytic vesicle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 753 Mm			1 221
+	Hs
		845940 SYTL5_HUMAN (1-753): 0: 584: 80.88		RB27A_HUMAN (1-221): 3.76e-82: 245: 95.93
+	Hs
		119864 SYTL5_HUMAN (1-753): 0: 584: 80.88		RB27B_HUMAN (1-221): 6e-78: 234: 71.95
+	Hs
		914240 SYTL5_HUMAN (1-753): 0: 584: 80.88		RB11A_HUMAN (3-220): 2.86e-77: 233: 34.84
+	Hs
		591482 SYTL5_HUMAN (1-753): 0: 584: 80.88		RAB3A_HUMAN (2-192): 8.9e-57: 181: 43.98
+	Hs
		591638 SYTL5_HUMAN (1-753): 0: 584: 80.88		RAB3B_HUMAN (2-190): 1.87e-54: 175: 43.92
+	Hs
		845942 SYTL4_HUMAN (5-753): 3.95e-157: 473: 37.14		RB27A_HUMAN (1-221): 3.76e-82: 245: 95.93
+	Mm
		1322328 SYTL4_MOUSE (5-753): 1.09e-153: 464: 37.22		RB27A_MOUSE (1-221): 3.76e-82: 245: 100.00
+	Hs
		119867 SYTL4_HUMAN (5-753): 3.95e-157: 473: 37.14		RB27B_HUMAN (1-221): 6e-78: 234: 71.95
+	Hs
		914274 SYTL4_HUMAN (5-753): 3.95e-157: 473: 37.14		RB11A_HUMAN (3-220): 2.86e-77: 233: 34.84
+	Mm
		1307925 SYTL4_MOUSE (5-753): 1.09e-153: 464: 37.22		RB27B_MOUSE (1-221): 4.19e-77: 232: 71.49
+	Mm
		722679 RP3A_MOUSE (11-752): 3.38e-140: 429: 17.65		RAB3D_MOUSE (2-221): 1.04e-85: 254: 40.46
+	Hs
		591484 SYTL4_HUMAN (5-753): 3.95e-157: 473: 37.14		RAB3A_HUMAN (2-192): 8.9e-57: 181: 43.98
+	Hs
		320135 SYTL4_HUMAN (5-753): 3.95e-157: 473: 37.14		RAB3D_HUMAN (2-190): 1.75e-56: 180: 43.92
+	Hs
		591654 SYTL4_HUMAN (5-753): 3.95e-157: 473: 37.14		RAB3B_HUMAN (2-190): 1.87e-54: 175: 43.92
+	Hs
		894790 SYTL4_HUMAN (5-753): 3.95e-157: 473: 37.14		RAB8A_HUMAN (6-187): 9.19e-54: 172: 46.70
+	Mm
		926098 SYTL4_MOUSE (5-753): 1.09e-153: 464: 37.22		RAB3A_MOUSE (2-192): 9.5e-57: 181: 43.98
+	Hs
		1273004 SYTL4_HUMAN (5-753): 3.95e-157: 473: 37.14		RAB8B_HUMAN (6-192): 3.9e-53: 171: 44.39
+	Mm
		877205 SYTL4_MOUSE (5-753): 1.09e-153: 464: 37.22		RAB8A_MOUSE (6-187): 1.15e-53: 172: 46.70
+	Mm
		812771 RP3A_MOUSE (11-752): 3.38e-140: 429: 17.65		RAB3C_MOUSE (2-190): 2.83e-56: 180: 43.92
+	Mm
		812770 RP3A_MOUSE (11-752): 3.38e-140: 429: 17.65		RAB8A_MOUSE (6-187): 1.15e-53: 172: 46.70