HitPredict

Interactor 1: TCAM1 (Q80UF7)
TIR domain-containing adapter molecule 1 (TICAM-1) (Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta) (TIR domain-containing adapter protein inducing IFN-beta)
Gene: Ticam1

Interactor 2: TLR4 (Q9QUK6)
Toll-like receptor 4 (CD antigen CD284)
Gene: TLR4

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.60 0.712

The method score is based on:

Property Details
Experiments 18772134, 25736436, 19898473, 19265160, 21911421
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005769 - early endosome
GO:0006809 - nitric oxide biosynthetic process
GO:0006954 - inflammatory response
GO:0010008 - endosome membrane
GO:0010628 - positive regulation of gene expression
and 17 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 732
Mm

1 835
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024