Interactor 1: ZNRF3 (Q4KLR8)
E3 ubiquitin-protein ligase ZNRF3 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ZNRF3) (Zinc/RING finger protein 3)
Gene: ZNRF3
Interactor 2: RSPO2 (Q5UE90)
R-spondin-2 (Roof plate-specific spondin-2) (XRspo2)
Gene: RSPO2
Species: Xenopus laevis
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.50 | 1.00 | 0.710 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24225776 |
| Identification Methods | x-ray crystallography, pull down |
| Interaction Type | association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Furin-like_2~ZNRF_3_ecto |
| Common GO terms | GO:0016055 - Wnt signaling pathway |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025