HitPredict

Interactor 1: URP2 (Q86UX7)
Fermitin family homolog 3 (Kindlin-3) (MIG2-like protein) (Unc-112-related protein 2)
Gene: FERMT3

Interactor 2: FERM1 (Q9BQL6)
Fermitin family homolog 1 (Kindlerin) (Kindlin syndrome protein) (Kindlin-1) (Unc-112-related protein 1)
Gene: FERMT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FERM_M~FERM_M, PH~PH
Common GO terms	GO:0005178 - integrin binding GO:0007160 - cell-matrix adhesion GO:0007229 - integrin-mediated signaling pathway
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 667 Hs			1 677
+	Hs
		1200427 URP2_HUMAN (1-667): 0: 1056: 100.00		FERM2_HUMAN (2-675): 0: 1013: 63.27
+	Hs
		1283788 FERM1_HUMAN (6-665): 0: 1023: 54.45		FERM2_HUMAN (2-675): 0: 1013: 63.27
+	Dm
		1374749 Q9VVD2_DROME (13-663): 0: 941: 39.34		UN112_DROME (9-675): 0: 948: 43.06
+	Ce
		1090248 UN112_CAEEL (9-663): 0: 869: 37.24		UN112_CAEEL (1-675): 0: 885: 42.39
+	Hs
		1377797 TLN1_HUMAN (462-655): 1.62e-72: 258: 23.29		TLN2_HUMAN (485-667): 7.43e-58: 214: 18.27