Protein: KLH38
Kelch-like protein 38

Gene: KLH38, KLHL38
Organism: Homo sapiens
Interactions: 106
UniProt ID: Q2WGJ6

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0031463 - Cul3-RING ubiquitin ligase complex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:1990756 - ubiquitin-like ligase-substrate adaptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1180796

ASB12
Ankyrin repeat and SOCS box protein 12

2

1

High-throughput

0.700

High

1180819

TRI54
Tripartite motif-containing protein 54

3

10

High-throughput

0.675

High

1180822

GO45
Golgin-45

3

0

High-throughput

0.646

High

1180784

NT2NA
Notch homolog 2 N-terminal-like protein A

2

4

High-throughput

0.633

High

1180832

KLH20
Kelch-like protein 20

1

20

High-throughput

0.621

High

300763

KRT38
Keratin, type I cuticular Ha8

3

6

High-throughput

0.616

High

685855

KRA59
Keratin-associated protein 5-9

3

10

High-throughput

0.616

High

848389

MAGA6
Melanoma-associated antigen 6

3

1

High-throughput

0.616

High

950258

KR107
Keratin-associated protein 10-7

3

9

High-throughput

0.616

High

950493

KR108
Keratin-associated protein 10-8

3

11

High-throughput

0.616

High

1145956

K1H1
Keratin, type I cuticular Ha1

3

6

High-throughput

0.616

High

1180791

TRI42
Tripartite motif-containing protein 42

3

12

High-throughput

0.616

High

1180793

USBP1
Harmonin-binding protein USHBP1

3

4

High-throughput

0.616

High

616699

ADA2C
Alpha-2C adrenergic receptor

2

1

High-throughput

0.606

High

1180786

TRI69
E3 ubiquitin-protein ligase TRIM69

2

3

High-throughput

0.606

High

1180800

TET5B
Terminal nucleotidyltransferase 5B

2

2

High-throughput

0.606

High

1180807

ATP5S
ATP synthase subunit s, mitochondrial

2

1

High-throughput

0.606

High

1180820

SPY4
Protein sprouty homolog 4

2

2

High-throughput

0.606

High

1180827

WWOX
WW domain-containing oxidoreductase

2

1

High-throughput

0.606

High

1180834

TACC3
Transforming acidic coiled-coil-containing protein 3

2

8

High-throughput

0.606

High

1180808

Q9BS75
Kelch-like protein 20

1

20

High-throughput

0.594

High

468435

HS90B
Heat shock protein HSP 90-beta

2

20

High-throughput

0.588

High

461542

HS90A
Heat shock protein HSP 90-alpha

2

20

High-throughput

0.584

High

1006250

CTG1B
Cancer/testis antigen 1

2

0

High-throughput

0.580

High

1180803

AP4AT
AP-4 complex accessory subunit Tepsin

2

0

High-throughput

0.580

High

1180805

PFD5
Prefoldin subunit 5

2

0

High-throughput

0.580

High

1180806

MDFI
MyoD family inhibitor

2

0

High-throughput

0.580

High

1180821

FTO
Alpha-ketoglutarate-dependent dioxygenase FTO

2

0

High-throughput

0.580

High

1180829

IKZF3
Zinc finger protein Aiolos

2

0

High-throughput

0.580

High

303136

RGS20
Regulator of G-protein signaling 20

1

2

High-throughput

0.573

High

893887

MEOX2
Homeobox protein MOX-2

1

3

High-throughput

0.573

High

1050435

UBE3A
Ubiquitin-protein ligase E3A

1

3

High-throughput

0.573

High

192376

GSC2
Homeobox protein goosecoid-2

2

3

High-throughput

0.553

High

300367

KRT34
Keratin, type I cuticular Ha4

2

6

High-throughput

0.553

High

353369

AGR2
Anterior gradient protein 2 homolog

2

1

High-throughput

0.553

High

699453

PROP
Properdin

2

1

High-throughput

0.553

High

1007518

KRT85
Keratin, type II cuticular Hb5

2

1

High-throughput

0.553

High

1059641

KRA11
Keratin-associated protein 1-1

2

11

High-throughput

0.553

High

1180775

KR132
Keratin-associated protein 13-2

2

1

High-throughput

0.553

High

1180776

GT253
Inactive glycosyltransferase 25 family member 3

2

1

High-throughput

0.553

High

1180778

K1C39
Keratin, type I cytoskeletal 39

2

7

High-throughput

0.553

High

1180780

GASP3
G protein-coupled receptor associated sorting protein 3

2

2

High-throughput

0.553

High

1180782

TXD11
Thioredoxin domain-containing protein 11

2

3

High-throughput

0.553

High

1180783

ATL4
ADAMTS-like protein 4

2

2

High-throughput

0.553

High

1180785

K1C27
Keratin, type I cytoskeletal 27

2

3

High-throughput

0.553

High

1180789

KRA13
Keratin-associated protein 1-3

2

11

High-throughput

0.553

High

1180797

KRT35
Keratin, type I cuticular Ha5

2

6

High-throughput

0.553

High

1180798

LHX4
LIM/homeobox protein Lhx4

2

3

High-throughput

0.553

High

1180799

TEKT1
Tektin-1

2

1

High-throughput

0.553

High

1180804

TRIB3
Tribbles homolog 3

2

6

High-throughput

0.553

High

1180812

KRA98
Keratin-associated protein 9-8

2

11

High-throughput

0.553

High

1180813

KRA93
Keratin-associated protein 9-3

2

11

High-throughput

0.553

High

1180814

KRA92
Keratin-associated protein 9-2

2

11

High-throughput

0.553

High

1180815

KR411
Keratin-associated protein 4-11

2

12

High-throughput

0.553

High

1180826

GOG6A
Golgin subfamily A member 6A

2

7

High-throughput

0.553

High

1180828

LHX3
LIM/homeobox protein Lhx3

2

3

High-throughput

0.553

High

1093831

TRAF1
TNF receptor-associated factor 1

1

0

High-throughput

0.549

High

1180790

NUDC3
NudC domain-containing protein 3

1

20

High-throughput

0.536

High

950767

KR109
Keratin-associated protein 10-9

1

9

High-throughput

0.523

High

1180777

K1C40
Keratin, type I cytoskeletal 40

1

6

High-throughput

0.523

High

1180802

TEKT5
Tektin-5

1

1

High-throughput

0.523

High

524

NBPFJ
NBPF family member NBPF19

1

1

High-throughput

0.481

High

226785

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

4

High-throughput

0.479

High

946122

MLF1
Myeloid leukemia factor 1

1

1

High-throughput

0.479

High

1126698

BECN1
Beclin-1

1

1

Small-scale

0.479

High

1153532

MLF2
Myeloid leukemia factor 2

1

1

High-throughput

0.479

High

1180810

AASD1
Alanyl-tRNA editing protein Aarsd1

1

1

High-throughput

0.479

High

1180830

CHIP
E3 ubiquitin-protein ligase CHIP

1

4

High-throughput

0.479

High

1180831

NUDC
Nuclear migration protein nudC

1

20

High-throughput

0.479

High

517009

NT2NC
Notch homolog 2 N-terminal-like protein C

1

4

High-throughput

0.470

High

1180817

KRA24
Keratin-associated protein 2-4

1

11

High-throughput

0.470

High

505323

KRA23
Keratin-associated protein 2-3

1

11

High-throughput

0.439

High

949888

KR103
Keratin-associated protein 10-3

1

11

High-throughput

0.439

High

1180787

KR131
Keratin-associated protein 13-1

1

1

High-throughput

0.439

High

75610

B3KTT5
cDNA FLJ38698 fis, clone KIDNE2002015, highly similar to HEAT SHOCK 70 kDa PROTEIN 1

1

6

High-throughput

0.437

High

76531

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

5

High-throughput

0.437

High

373961

RASN
GTPase NRas

1

2

High-throughput

0.437

High

731349

STIP1
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.437

High

1180781

Q6PK50
HSP90AB1 protein

1

20

High-throughput

0.437

High

1180801

Q96BE0
Heat shock cognate 71 kDa protein

1

10

High-throughput

0.437

High

1180824

CYBP
Calcyclin-binding protein

1

2

High-throughput

0.437

High

70227

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

217099

MS18B
Protein Mis18-beta

2

0

High-throughput

0.316

High

587094

ITF2
Transcription factor 4

2

0

High-throughput

0.316

High

1037720

PAX5
Paired box protein Pax-5

2

0

High-throughput

0.316

High

1093625

MKRN3
E3 ubiquitin-protein ligase makorin-3

2

0

High-throughput

0.316

High

1157167

S15A2
Solute carrier family 15 member 2

2

0

High-throughput

0.316

High

1159375

ECM1
Extracellular matrix protein 1

2

0

High-throughput

0.316

High

1160360

OBF1
POU domain class 2-associating factor 1

2

0

High-throughput

0.316

High

1177914

RSPO4
R-spondin-4

2

0

High-throughput

0.316

High

1180773

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

1180779

MORN3
MORN repeat-containing protein 3

2

0

High-throughput

0.316

High

1180788

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.316

High

1180794

WFDC5
WAP four-disulfide core domain protein 5

2

0

High-throughput

0.316

High

1180795

POF1B
Protein POF1B

2

0

High-throughput

0.316

High

1180809

HDHD3
Haloacid dehalogenase-like hydrolase domain-containing protein 3

2

0

High-throughput

0.316

High

1180816

KRA33
Keratin-associated protein 3-3

2

0

High-throughput

0.316

High

1180818

PBX4
Pre-B-cell leukemia transcription factor 4

2

0

High-throughput

0.316

High

1180823

CFA68
Cilia- and flagella-associated protein 68

2

0

High-throughput

0.316

High

1180825

PLS4
Phospholipid scramblase 4

2

0

High-throughput

0.316

High

1180833

T10B
Mitochondrial import inner membrane translocase subunit Tim10 B

2

0

High-throughput

0.316

High

283487

TAD2A
Transcriptional adapter 2-alpha

1

0

High-throughput

0.299

High

1180811

ZN341
Zinc finger protein 341

1

0

High-throughput

0.299

High

959479

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.251

Low

1180774

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

1180792

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025