HitPredict

Interactor 1: ZCH18 (Q86VM9)
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)
Gene: ZC3H18

Interactor 2: SRSF8 (Q9BRL6)
Serine/arginine-rich splicing factor 8 (Pre-mRNA-splicing factor SRP46) (Splicing factor SRp46) (Splicing factor, arginine/serine-rich 2B)
Gene: SRSF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 29298432, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0016607 - nuclear speck
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 953 Hs			1 282
+	Hs
		964019 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		SRSF2_HUMAN (1-100): 1.3e-41: 144: 80.00
+	Hs
		1201760 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		PPIE_HUMAN (16-102): 3.36e-32: 122: 35.63
+	Hs
		1020284 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		ELAV2_HUMAN (2-99): 7.35e-24: 100: 22.45
+	Hs
		516580 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		PABP1_HUMAN (2-103): 1.99e-20: 92.9: 18.63
+	Hs
		1047880 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		CIRBP_HUMAN (16-160): 2.29e-19: 85: 33.79
+	Hs
		964025 SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14		SRSF2_HUMAN (1-100): 1.3e-41: 144: 80.00
+	Hs
		1246388 THOC2_HUMAN (248-635): 6.8e-20: 98.2: 14.15		PPIE_HUMAN (16-102): 3.36e-32: 122: 35.63
+	Hs
		1357564 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		PPIE_HUMAN (16-102): 3.36e-32: 122: 35.63
+	Hs
		1222876 SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14		PPIE_HUMAN (16-102): 3.36e-32: 122: 35.63
+	Hs
		1020354 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		ELAV2_HUMAN (2-99): 7.35e-24: 100: 22.45
+	Hs
		516749 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		PABP1_HUMAN (2-103): 1.99e-20: 92.9: 18.63
+	Hs
		1031405 TITIN_HUMAN (139-952): 5.65e-14: 79: 9.54		PABP4_HUMAN (2-103): 9.14e-22: 96.7: 19.61
+	Hs
		516609 TITIN_HUMAN (139-952): 5.65e-14: 79: 9.54		PABP1_HUMAN (2-103): 1.99e-20: 92.9: 18.63
+	Hs
		965152 ANK2_HUMAN (498-952): 3.04e-11: 70.1: 14.63		PABP3_HUMAN (2-103): 2.88e-19: 89.4: 19.61