Protein: VAS1
V-type proton ATPase subunit S1 (V-ATPase subunit S1) (Protein XAP-3) (V-ATPase Ac45 subunit) (V-ATPase S1 accessory protein) (Vacuolar proton pump subunit S1)

Gene: VAS1, ATP6AP1
Organism: Homo sapiens
Interactions: 134
UniProt ID: Q15904

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001671 - ATPase activator activity
GO:0005765 - lysosomal membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

292638

RENR
Renin receptor

7

1

Small-scale

0.965

High

961524

VA0D1
V-type proton ATPase subunit d 1

3

2

High-throughput

0.861

High

692199

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

2

0

High-throughput

0.770

High

1155290

VPP2
V-type proton ATPase 116 kDa subunit a 2

4

6

High-throughput

0.697

High

1155251

VPP1
V-type proton ATPase 116 kDa subunit a 1

4

6

High-throughput

0.691

High

1155237

K2013
Uncharacterized protein KIAA2013

3

1

High-throughput

0.662

High

698694

CALX
Calnexin

3

1

High-throughput

0.657

High

1155275

PICK1
PRKCA-binding protein

3

0

High-throughput

0.638

High

1155242

VA0D2
V-type proton ATPase subunit d 2

1

2

High-throughput

0.618

High

170772

CLGN
Calmegin

2

1

High-throughput

0.601

High

538600

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

2

1

High-throughput

0.601

High

1106779

VPP3
V-type proton ATPase 116 kDa subunit a 3

2

6

High-throughput

0.601

High

1155270

VPP4
V-type proton ATPase 116 kDa subunit a 4

2

6

High-throughput

0.601

High

1155230

SYVN1
E3 ubiquitin-protein ligase synoviolin

2

2

Small-scale

0.595

High

901260

RAB7A
Ras-related protein Rab-7a

2

0

High-throughput

0.585

High

337097

NPT2B
Sodium-dependent phosphate transport protein 2B

2

0

High-throughput

0.576

High

341208

VATG2
V-type proton ATPase subunit G 2

2

1

High-throughput

0.571

High

241790

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

1155276

T106B
Transmembrane protein 106B

2

0

Small-scale

0.559

High

396193

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

186472

VA0E1
V-type proton ATPase subunit e 1

1

1

High-throughput

0.536

High

276835

VATG1
V-type proton ATPase subunit G 1

1

1

High-throughput

0.536

High

380430

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

1

High-throughput

0.536

High

800494

VATA
V-type proton ATPase catalytic subunit A

1

1

High-throughput

0.536

High

1155220

VATF
V-type proton ATPase subunit F

1

1

High-throughput

0.536

High

1155267

GORS2
Golgi reassembly-stacking protein 2

1

1

High-throughput

0.536

High

410870

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

0

High-throughput

0.518

High

999641

HBA
Hemoglobin subunit alpha

1

0

High-throughput

0.518

High

64949

ARRD5
Arrestin domain-containing protein 5

1

0

High-throughput

0.513

High

168406

NCTR3
Natural cytotoxicity triggering receptor 3

1

0

High-throughput

0.513

High

637020

VATB2
V-type proton ATPase subunit B, brain isoform

1

0

High-throughput

0.513

High

773520

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.513

High

908013

VAMP7
Vesicle-associated membrane protein 7

1

0

High-throughput

0.513

High

1102790

UT1
Urea transporter 1

1

0

High-throughput

0.513

High

1155238

CKLF8
CKLF-like MARVEL transmembrane domain-containing protein 8

1

0

High-throughput

0.513

High

1155245

T185A
Transmembrane protein 185A

1

0

High-throughput

0.513

High

1155257

SERC2
Serine incorporator 2

1

0

High-throughput

0.513

High

1155269

CERS4
Ceramide synthase 4

1

0

High-throughput

0.513

High

1155284

PILRB
Paired immunoglobulin-like type 2 receptor beta

1

0

High-throughput

0.513

High

1155289

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

1155228

RHOU
Rho-related GTP-binding protein RhoU

1

6

High-throughput

0.501

High

282943

NR1I2
Nuclear receptor subfamily 1 group I member 2

1

1

High-throughput

0.494

High

185731

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

48640

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.479

High

126615

RHOD
Rho-related GTP-binding protein RhoD

1

7

High-throughput

0.479

High

192494

INSI1
Insulin-induced gene 1 protein

1

1

High-throughput

0.479

High

466274

RHOC
Rho-related GTP-binding protein RhoC

1

5

High-throughput

0.479

High

581070

RAC2
Ras-related C3 botulinum toxin substrate 2

1

5

High-throughput

0.479

High

910071

RND2
Rho-related GTP-binding protein RhoN

1

7

High-throughput

0.479

High

953470

RAC3
Ras-related C3 botulinum toxin substrate 3

1

5

High-throughput

0.479

High

955211

CDC42
Cell division control protein 42 homolog

1

6

High-throughput

0.479

High

962087

RHOA
Transforming protein RhoA

1

6

High-throughput

0.479

High

1015462

RHOG
Rho-related GTP-binding protein RhoG

1

5

High-throughput

0.479

High

1155234

GOLI
E3 ubiquitin-protein ligase RNF130

1

1

High-throughput

0.479

High

1155235

MIRO2
Mitochondrial Rho GTPase 2

1

8

High-throughput

0.479

High

1155249

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.479

High

1155255

DNJC1
DnaJ homolog subfamily C member 1

1

1

High-throughput

0.479

High

1155261

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.479

High

1155266

DJC25
DnaJ homolog subfamily C member 25

1

1

High-throughput

0.479

High

1155271

RHOF
Rho-related GTP-binding protein RhoF

1

7

High-throughput

0.479

High

1155285

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.479

High

1155291

INSI2
Insulin-induced gene 2 protein

1

1

High-throughput

0.479

High

178277

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

208508

PJA2
E3 ubiquitin-protein ligase Praja-2

1

0

Small-scale

0.458

High

218223

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

337949

CNEP1
CTD nuclear envelope phosphatase 1

1

0

High-throughput

0.458

High

580638

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

762331

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

0

High-throughput

0.458

High

820650

CEAM6
Cell adhesion molecule CEACAM6

1

0

High-throughput

0.458

High

1125451

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.458

High

1155218

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.458

High

1155219

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

0

High-throughput

0.458

High

1155221

MKS3
Meckelin

1

0

High-throughput

0.458

High

1155223

LTOR1
Ragulator complex protein LAMTOR1

1

0

Small-scale

0.458

High

1155229

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

1155236

TM192
Transmembrane protein 192

1

0

High-throughput

0.458

High

1155240

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.458

High

1155241

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

1155244

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.458

High

1155247

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.458

High

1155252

PLD4
5'-3' exonuclease PLD4

1

0

High-throughput

0.458

High

1155273

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

1155278

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

1155281

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.458

High

1155282

S12A6
Solute carrier family 12 member 6

1

0

Small-scale

0.458

High

1155288

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

380290

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

1

High-throughput

0.445

High

1155248

MOT10
Monocarboxylate transporter 10

1

2

High-throughput

0.445

High

1155260

GORS1
Golgi reassembly-stacking protein 1

1

1

High-throughput

0.445

High

1155263

S46A2
Solute carrier family 46 member 2

1

2

High-throughput

0.445

High

611141

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

1

High-throughput

0.437

High

1155225

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

1155254

TECT2
Tectonic-2

1

1

High-throughput

0.437

High

127093

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.426

High

609685

LEG3
Galectin-3

1

0

High-throughput

0.426

High

834973

S19A1
Reduced folate transporter

1

0

High-throughput

0.426

High

954394

SNP25
Synaptosomal-associated protein 25

1

0

Small-scale

0.426

High

1052994

VMAT2
Synaptic vesicular amine transporter

1

0

High-throughput

0.426

High

1093511

TRDN
Triadin

1

0

High-throughput

0.426

High

1155224

PKHA7
Pleckstrin homology domain-containing family A member 7

1

0

High-throughput

0.426

High

1155227

LHPL2
LHFPL tetraspan subfamily member 2 protein

1

0

High-throughput

0.426

High

1155239

S35F6
Solute carrier family 35 member F6

1

0

High-throughput

0.426

High

1155250

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.426

High

1155253

S47A1
Multidrug and toxin extrusion protein 1

1

0

High-throughput

0.426

High

1155256

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

0

High-throughput

0.426

High

1155259

SC6A7
Sodium-dependent proline transporter

1

0

High-throughput

0.426

High

1155264

LMA2L
VIP36-like protein

1

0

High-throughput

0.426

High

1155272

SO1B3
Solute carrier organic anion transporter family member 1B3

1

0

High-throughput

0.426

High

1155280

RHCG
Ammonium transporter Rh type C

1

0

High-throughput

0.426

High

1155286

FLVC2
Choline/ethanolamine transporter FLVCR2

1

0

High-throughput

0.426

High

397960

ANGI
Angiogenin

1

0

High-throughput

0.282

High

1155216

DREB
Drebrin

1

0

High-throughput

0.279

Low

1155217

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.279

Low

1155222

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

0

High-throughput

0.279

Low

1155246

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.279

Low

1155279

MYEF2
Myelin expression factor 2

1

0

High-throughput

0.279

Low

1155283

DKKL1
Dickkopf-like protein 1

1

0

High-throughput

0.279

Low

843590

HD
Huntingtin

1

0

High-throughput

0.268

Low

105996

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

385783

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.249

Low

1004618

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1155215

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

1155226

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1155231

LBN
Limbin

1

0

High-throughput

0.249

Low

1155232

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1155258

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.249

Low

1155262

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.249

Low

1155274

FBX6
F-box only protein 6

1

0

High-throughput

0.249

Low

1155277

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1155233

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

0

High-throughput

0.232

Low

1155243

S43A3
Equilibrative nucleobase transporter 1

1

0

High-throughput

0.232

Low

1155265

METL9
Protein-L-histidine N-pros-methyltransferase

1

0

High-throughput

0.232

Low

1155268

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.232

Low

1155287

WASC3
WASH complex subunit 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025