HitPredict

Interactor 1: LCA5 (Q86VQ0)
Lebercilin (Leber congenital amaurosis 5 protein)
Gene: LCA5

Interactor 2: DYL2 (Q96FJ2)
Dynein light chain 2, cytoplasmic (8 kDa dynein light chain b) (DLC8b) (Dynein light chain LC8-type 2)
Gene: DYNLL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26638075, 27173435, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005929 - cilium
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 697 Hs			1 89
+	Hs
		928368 LCA5_HUMAN (1-697): 1.31e-79: 269: 100.00		DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26
+	Hs
		1189784 MYH14_HUMAN (48-530): 2.28e-23: 108: 14.09		DYL2_HUMAN (1-89): 7.09e-47: 146: 100.00
+	Hs
		551662 DESP_HUMAN (31-635): 8.92e-16: 83.9: 12.21		DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26
+	Hs
		928339 MRCKG_HUMAN (80-478): 2.56e-10: 66.1: 13.40		DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26
+	Hs
		928410 RBCC1_HUMAN (123-533): 3.58e-10: 65.8: 16.55		DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26
+	Hs
		148656 CTRO_HUMAN (46-497): 3.91e-10: 65.4: 12.14		DYL1_HUMAN (1-89): 1.8e-47: 147: 93.26
+	Hs
		1150626 MRCKG_HUMAN (80-478): 2.56e-10: 66.1: 13.40		DYL2_HUMAN (1-89): 7.09e-47: 146: 100.00