Protein: HCDH
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HCDH) (EC 1.1.1.35) (Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase) (Short-chain 3-hydroxyacyl-CoA dehydrogenase)

Gene: HCDH, HADH
Organism: Homo sapiens
Interactions: 73
UniProt ID: Q16836

Gene Ontology (top 5):
GO:0003857 - 3-hydroxyacyl-CoA dehydrogenase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1088159

HCDH
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

1

3

Small-scale

0.647

High

1045764

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

2

High-throughput

0.618

High

262830

CISY
Citrate synthase, mitochondrial

2

1

High-throughput

0.584

High

1086583

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

1

High-throughput

0.584

High

1088163

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

238272

RAD1
Cell cycle checkpoint protein RAD1

1

0

High-throughput

0.513

High

1088164

NEK7
Serine/threonine-protein kinase Nek7

1

0

High-throughput

0.513

High

1088173

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

0

High-throughput

0.513

High

394814

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

894066

CDC42
Cell division control protein 42 homolog

1

2

High-throughput

0.501

High

1088187

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

59193

VWA8
von Willebrand factor A domain-containing protein 8

1

2

High-throughput

0.479

High

63366

MET15
12S rRNA N4-methylcytidine

1

1

High-throughput

0.479

High

196311

PJA2
E3 ubiquitin-protein ligase Praja-2

1

1

Small-scale

0.479

High

227599

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.479

High

264916

MPPB
Mitochondrial-processing peptidase subunit beta

1

4

High-throughput

0.479

High

327448

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

1

High-throughput

0.479

High

384922

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.479

High

440538

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.479

High

486535

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

1

High-throughput

0.479

High

499786

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.479

High

552847

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

647599

MK03
Mitogen-activated protein kinase 3

1

2

Small-scale

0.479

High

651337

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

720587

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

777577

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

789815

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

1

High-throughput

0.479

High

799235

EFTS
Elongation factor Ts, mitochondrial

1

1

High-throughput

0.479

High

803125

IF2M
Translation initiation factor IF-2, mitochondrial

1

3

High-throughput

0.479

High

827400

EFTU
Elongation factor Tu, mitochondrial

1

2

High-throughput

0.479

High

874989

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

919092

RAN
GTP-binding nuclear protein Ran

1

1

High-throughput

0.479

High

958924

TFAM
Transcription factor A, mitochondrial

1

3

High-throughput

0.479

High

981266

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

1

High-throughput

0.479

High

990082

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

High-throughput

0.479

High

1014382

MPPA
Mitochondrial-processing peptidase subunit alpha

1

4

High-throughput

0.479

High

1020440

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

1

High-throughput

0.479

High

1043021

CUL4A
Cullin-4A

1

1

High-throughput

0.479

High

1050963

ICT1
Large ribosomal subunit protein mL62

1

1

High-throughput

0.479

High

1088161

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

1088162

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

4

High-throughput

0.479

High

1088165

FAKD4
FAST kinase domain-containing protein 4

1

4

High-throughput

0.479

High

1088166

RRFM
Ribosome-recycling factor, mitochondrial

1

1

High-throughput

0.479

High

1088167

EFGM
Elongation factor G, mitochondrial

1

2

High-throughput

0.479

High

1088169

BAG1
BAG family molecular chaperone regulator 1

1

1

High-throughput

0.479

High

1088170

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

1

High-throughput

0.479

High

1088171

RT26
Small ribosomal subunit protein mS26

1

1

High-throughput

0.479

High

1088172

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

2

High-throughput

0.479

High

1088174

MTRFR
Mitochondrial translation release factor in rescue

1

4

High-throughput

0.479

High

1088175

MTG2
Mitochondrial ribosome-associated GTPase 2

1

1

High-throughput

0.479

High

1088176

MET17
Ribosome assembly protein METTL17, mitochondrial

1

1

High-throughput

0.479

High

1088177

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

1

High-throughput

0.479

High

1088179

ANLN
Anillin

1

1

High-throughput

0.479

High

1088180

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

4

High-throughput

0.479

High

1088182

MRES1
Mitochondrial transcription rescue factor 1

1

1

High-throughput

0.479

High

1088184

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

4

High-throughput

0.479

High

1088185

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1088186

RM11
Large ribosomal subunit protein uL11m

1

1

High-throughput

0.479

High

426926

ADH1A
Alcohol dehydrogenase 1A

1

0

High-throughput

0.460

High

786361

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

High-throughput

0.460

High

1088183

FXL17
F-box/LRR-repeat protein 17

1

0

Small-scale

0.460

High

130915

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

Small-scale

0.458

High

1085296

FSCN1
Fascin

1

0

High-throughput

0.458

High

1088168

CGRF1
Cell growth regulator with RING finger domain protein 1

1

0

High-throughput

0.458

High

1088181

MARH2
E3 ubiquitin-protein ligase MARCHF2

1

0

High-throughput

0.458

High

833743

CLK1
Dual specificity protein kinase CLK1

1

2

High-throughput

0.457

High

122265

RN103
E3 ubiquitin-protein ligase RNF103

1

2

High-throughput

0.437

High

908629

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

951030

RHOG
Rho-related GTP-binding protein RhoG

1

2

High-throughput

0.437

High

1066183

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.437

High

1088160

RNFT1
E3 ubiquitin-protein ligase RNFT1

1

1

High-throughput

0.437

High

1088178

RTN4
Reticulon-4

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024