HitPredict

Interactor 1: HOOK3 (Q86VS8)
Protein Hook homolog 3 (h-hook3) (hHK3)
Gene: HOOK3

Interactor 2: RAD50 (Q92878)
DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)
Gene: RAD50

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	28718761
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 718 Hs			1 1312
+	Hs
		1272054 HOOK1_HUMAN (196-712): 4.3e-14: 78.1: 12.98		RAD50_HUMAN (1-1312): 1.28e-115: 394: 100.00
+	Hs
		1113802 HOOK3_HUMAN (1-718): 3.74e-57: 209: 100.00		GRDN_HUMAN (530-1217): 5.01e-21: 102: 12.32
+	Hs
		725198 HOOK3_HUMAN (1-718): 3.74e-57: 209: 100.00		MYH10_HUMAN (44-596): 1.31e-16: 88.3: 13.20
+	Hs
		724687 MYH10_HUMAN (308-718): 3.14e-15: 82.3: 10.71		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		528432 MYH8_HUMAN (289-718): 2.07e-17: 89.3: 10.27		MYH13_HUMAN (524-1245): 6.07e-22: 105: 10.56
+	Hs
		522657 MYH4_HUMAN (279-718): 3.71e-14: 78.7: 12.89		MYH7_HUMAN (524-1249): 1.05e-24: 114: 10.81
+	Rn
		361106 MYH6_RAT (349-718): 2.08e-13: 76.2: 11.97		MYH6_RAT (524-1204): 1.16e-24: 114: 10.56
+	Hs
		1268126 MRCKB_HUMAN (401-706): 2.71e-13: 75.8: 13.67		MY18A_HUMAN (158-674): 1.53e-19: 97.7: 14.45
+	Hs
		528435 MYH8_HUMAN (289-718): 2.07e-17: 89.3: 10.27		MYH4_HUMAN (785-1235): 1.33e-14: 81.7: 12.88
+	Hs
		725095 MYH10_HUMAN (308-718): 3.14e-15: 82.3: 10.71		MYH10_HUMAN (44-596): 1.31e-16: 88.3: 13.20
+	Hs
		725097 MYH10_HUMAN (308-718): 3.14e-15: 82.3: 10.71		MYH11_HUMAN (46-651): 5.68e-16: 86: 8.67
+	Rn
		222476 MRCKA_RAT (328-718): 3.5e-21: 101: 14.08		MRCKB_RAT (445-944): 1.2e-09: 65.1: 19.78
+	Rn
		92843 ROCK2_RAT (102-662): 6.69e-13: 74.6: 15.76		CTRO_RAT (547-1141): 7.3e-16: 85.7: 13.16
+	Hs
		502933 MYH4_HUMAN (279-718): 3.71e-14: 78.7: 12.89		MYH3_HUMAN (785-1231): 2.95e-12: 74: 11.60
+	Hs
		148461 MYH10_HUMAN (308-718): 3.14e-15: 82.3: 10.71		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15
+	Hs
		148466 MYH11_HUMAN (308-712): 6.49e-15: 81.2: 8.94		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15
+	Hs
		149399 HOOK1_HUMAN (196-712): 4.3e-14: 78.1: 12.98		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15
+	Rn
		1186812 MRCKB_RAT (70-519): 1.55e-13: 76.5: 13.03		MRCKB_RAT (445-944): 1.2e-09: 65.1: 19.78