HitPredict

Interactor 1: PP6R3 (Q5H9R7)
Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3) (Sporulation-induced transcript 4-associated protein SAPL)
Gene: PPP6R3

Interactor 2: BRSK1 (Q8TDC3)
Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1)
Gene: BRSK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 873 Hs			1 778
+	Hs
		1204756 PP6R3_HUMAN (1-873): 0: 870: 100.00		BRSK2_HUMAN (17-778): 3.01e-175: 522: 70.54
+	Hs
		1350987 PP6R1_HUMAN (1-872): 0: 675: 43.30		BRSK1_HUMAN (1-778): 0: 652: 100.00
+	Hs
		930718 PP6R3_HUMAN (1-873): 0: 870: 100.00		AAPK2_HUMAN (23-561): 2.68e-143: 434: 28.18
+	Hs
		273648 PP6R2_HUMAN (1-870): 0: 783: 45.90		MARK3_HUMAN (11-711): 1.25e-166: 501: 26.75
+	Hs
		273683 PP6R2_HUMAN (1-870): 0: 783: 45.90		MARK2_HUMAN (9-711): 8.24e-156: 474: 27.00
+	Hs
		273721 PP6R2_HUMAN (1-870): 0: 783: 45.90		MARK1_HUMAN (4-711): 7.92e-151: 462: 25.79
+	Mm
		1229954 PP6R1_MOUSE (1-873): 0: 686: 44.03		BRSK2_MOUSE (25-778): 1.36e-176: 526: 71.15