HitPredict

Interactor 1: Q8C9M8 (Q8C9M8)
Zinc finger protein 446
Gene: Zfp446

Interactor 2: ISL2 (Q9CXV0)
Insulin gene enhancer protein ISL-2 (Islet-2)
Gene: ISL2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	20211142
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0046872 - metal ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 523 Mm			1 359
+	Mm
		103325 G3X9U2_MOUSE (101-523): 1.01e-120: 362: 100.00		ISL2_MOUSE (1-359): 1.69e-85: 264: 100.00
+	Mm
		1208071 Q8C9M8_MOUSE (1-523): 6.42e-130: 390: 100.00		LHX9_MOUSE (10-325): 4.1e-59: 197: 27.22
+	Mm
		103327 G3X9U2_MOUSE (101-523): 1.01e-120: 362: 100.00		LHX9_MOUSE (10-325): 4.1e-59: 197: 27.22
+	Hs
		822658 ZKSC4_HUMAN (100-523): 1.08e-115: 354: 26.35		LHX1_HUMAN (26-356): 5.2e-58: 195: 26.54
+	Mm
		292005 Q8C9M8_MOUSE (1-523): 6.42e-130: 390: 100.00		LMX1B_MOUSE (7-83): 7.55e-18: 85.8: 19.48
+	Mm
		1129997 ZSC26_MOUSE (123-523): 1.51e-103: 320: 26.15		Q8VD35_MOUSE (155-354): 1.21e-42: 151: 18.64
+	Mm
		103322 G3X9U2_MOUSE (101-523): 1.01e-120: 362: 100.00		LMX1B_MOUSE (7-83): 7.55e-18: 85.8: 19.48
+	Hs
		903756 ZN397_HUMAN (3-442): 9.85e-74: 244: 13.08		LMO4_HUMAN (15-165): 1.89e-54: 177: 38.13
+	Hs
		638487 ZNF84_HUMAN (118-389): 8.95e-69: 236: 9.39		RBTN1_HUMAN (17-144): 5.24e-53: 174: 38.17
+	Hs
		304690 ZN202_HUMAN (336-523): 2.32e-48: 179: 21.62		LMO4_HUMAN (15-165): 1.89e-54: 177: 38.13
+	Hs
		822701 ZSC21_HUMAN (3-387): 8.35e-41: 155: 11.03		LHX1_HUMAN (26-356): 5.2e-58: 195: 26.54
+	Hs
		846679 ZNF84_HUMAN (118-389): 8.95e-69: 236: 9.39		LMO3_HUMAN (27-148): 1.79e-26: 104: 40.16
+	Hs
		154549 ZN213_HUMAN (465-523): 2.6e-27: 116: 35.59		LMO4_HUMAN (15-165): 1.89e-54: 177: 38.13
+	Hs
		563560 ZNF24_HUMAN (445-523): 5.08e-29: 119: 29.11		RBTN1_HUMAN (17-144): 5.24e-53: 174: 38.17
+	Hs
		1078405 ZKSC8_HUMAN (123-390): 5.62e-48: 176: 10.26		LMO3_HUMAN (27-148): 1.79e-26: 104: 40.16
+	Hs
		903758 ZN675_HUMAN (124-331): 8.07e-23: 103: 8.45		LMO4_HUMAN (15-165): 1.89e-54: 177: 38.13
+	Hs
		1357658 ZSC21_HUMAN (3-387): 8.35e-41: 155: 11.03		LHX6_HUMAN (7-84): 1.63e-12: 69.6: 19.23
+	Hs
		182424 ZSC9_HUMAN (492-523): 2.28e-10: 64.3: 40.63		LMO3_HUMAN (27-148): 1.79e-26: 104: 40.16