Interactor 1: LRRK2 (Q5S006)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-)
Gene: LRRK2
Interactor 2: FADD (Q61160)
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity)
Gene: FADD
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19176810 |
| Identification Methods | anti bait coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DED~Pkinase |
| Common GO terms | GO:0032760 - positive regulation of tumor necrosis factor production GO:0044877 - protein-containing complex binding |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
