Download interactions: TXT MITAB-2.5
| Interaction | Interactor | Experiments | Homologs | Category | Interaction Score |
Confidence |
|---|---|---|---|---|---|---|
|
CASP8
Caspase-8 |
59 |
20 |
Small-scale |
0.997 | High |
|
|
TNR6
Tumor necrosis factor receptor superfamily member 6 |
35 |
20 |
Small-scale |
0.994 | High |
|
|
RIPK1
Receptor-interacting serine/threonine-protein kinase 1 |
33 |
20 |
Small-scale |
0.993 | High |
|
|
CFLAR
CASP8 and FADD-like apoptosis regulator |
13 |
16 |
Small-scale |
0.981 | High |
|
|
TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein |
14 |
5 |
Small-scale |
0.980 | High |
|
|
TR10A
Tumor necrosis factor receptor superfamily member 10A |
13 |
20 |
Small-scale |
0.977 | High |
|
|
TR10B
Tumor necrosis factor receptor superfamily member 10B |
13 |
20 |
Small-scale |
0.977 | High |
|
|
FADD
FAS-associated death domain protein |
10 |
16 |
Small-scale |
0.970 | High |
|
|
CASPA
Caspase-10 |
7 |
20 |
Small-scale |
0.968 | High |
|
|
RIPK3
Receptor-interacting serine/threonine-protein kinase 3 |
7 |
18 |
Small-scale |
0.949 | High |
|
|
TNR1A
Tumor necrosis factor receptor superfamily member 1A |
6 |
20 |
Small-scale |
0.928 | High |
|
|
DEDD
Death effector domain-containing protein |
3 |
6 |
Small-scale |
0.857 | High |
|
|
MYD88
Myeloid differentiation primary response protein MyD88 |
3 |
7 |
Small-scale |
0.829 | High |
|
|
PLK1
Serine/threonine-protein kinase PLK1 |
1 |
2 |
Small-scale |
0.780 | High |
|
|
PEA15
Astrocytic phosphoprotein PEA-15 |
2 |
1 |
Small-scale |
0.768 | High |
|
|
TNF10
Tumor necrosis factor ligand superfamily member 10 |
16 |
16 |
Small-scale |
0.759 | High |
|
|
DAPK1
Death-associated protein kinase 1 |
2 |
10 |
Small-scale |
0.754 | High |
|
|
PIDD1
p53-induced death domain-containing protein 1 |
2 |
5 |
Small-scale |
0.754 | High |
|
|
TNFL6
Tumor necrosis factor ligand superfamily member 6 |
6 |
16 |
Small-scale |
0.726 | High |
|
|
IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha |
1 |
9 |
High-throughput |
0.691 | High |
|
|
KC1A
Casein kinase I isoform alpha |
1 |
2 |
High-throughput |
0.691 | High |
|
|
KC1D
Casein kinase I isoform delta |
1 |
2 |
High-throughput |
0.691 | High |
|
|
LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2 |
1 |
5 |
Small-scale |
0.691 | High |
|
|
IL37
Interleukin-37 |
3 |
3 |
High-throughput |
0.667 | High |
|
|
KPCZ
Protein kinase C zeta type |
1 |
4 |
Small-scale |
0.665 | High |
|
|
ULK3
Serine/threonine-protein kinase ULK3 |
1 |
0 |
High-throughput |
0.656 | High |
|
|
TNAP3
Tumor necrosis factor alpha-induced protein 3 |
3 |
11 |
Small-scale |
0.656 | High |
|
|
NEMO
NF-kappa-B essential modulator |
2 |
9 |
Small-scale |
0.628 | High |
|
|
IRAK1
Interleukin-1 receptor-associated kinase 1 |
1 |
2 |
Small-scale |
0.618 | High |
|
|
HIPK3
Homeodomain-interacting protein kinase 3 |
1 |
8 |
Small-scale |
0.618 | High |
|
|
NLRC4
NLR family CARD domain-containing protein 4 |
1 |
4 |
Small-scale |
0.618 | High |
|
|
TANK
TRAF family member-associated NF-kappa-B activator |
2 |
4 |
Small-scale |
0.611 | High |
|
|
SDCB1
Syntenin-1 |
2 |
2 |
High-throughput |
0.606 | High |
|
|
MAVS
Mitochondrial antiviral-signaling protein |
2 |
3 |
Small-scale |
0.601 | High |
|
|
NACA
Nascent polypeptide-associated complex subunit alpha |
2 |
0 |
Small-scale |
0.598 | High |
|
|
PARK7
Parkinson disease protein 7 |
1 |
1 |
Small-scale |
0.597 | High |
|
|
RT29
Small ribosomal subunit protein mS29 |
2 |
0 |
Small-scale |
0.593 | High |
|
|
EZRI
Ezrin |
2 |
12 |
Small-scale |
0.588 | High |
|
|
ATG5
Autophagy protein 5 |
1 |
4 |
Small-scale |
0.586 | High |
|
|
BTG1
Protein BTG1 |
2 |
0 |
High-throughput |
0.580 | High |
|
|
RNF4
E3 ubiquitin-protein ligase RNF4 |
2 |
0 |
High-throughput |
0.580 | High |
|
|
DDT4L
DNA damage-inducible transcript 4-like protein |
2 |
0 |
High-throughput |
0.580 | High |
|
|
RO52
E3 ubiquitin-protein ligase TRIM21 |
1 |
6 |
Small-scale |
0.578 | High |
|
|
CHIP
E3 ubiquitin-protein ligase CHIP |
1 |
2 |
Small-scale |
0.578 | High |
|
|
MK01
Mitogen-activated protein kinase 1 |
1 |
3 |
High-throughput |
0.575 | High |
|
|
MK08
Mitogen-activated protein kinase 8 |
1 |
6 |
Small-scale |
0.575 | High |
|
|
GDIR1
Rho GDP-dissociation inhibitor 1 |
1 |
2 |
Small-scale |
0.575 | High |
|
|
SPOP
Speckle-type POZ protein |
2 |
0 |
Small-scale |
0.561 | High |
|
|
RAP1A
Ras-related protein Rap-1A |
1 |
5 |
Small-scale |
0.561 | High |
|
|
MKRN1
E3 ubiquitin-protein ligase makorin-1 |
1 |
1 |
Small-scale |
0.561 | High |
|
|
FAF1
FAS-associated factor 1 |
1 |
2 |
Small-scale |
0.561 | High |
|
|
TRAF6
TNF receptor-associated factor 6 |
1 |
20 |
Small-scale |
0.561 | High |
|
|
PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
1 |
0 |
Small-scale |
0.537 | High |
|
|
RHOQ
Rho-related GTP-binding protein RhoQ |
1 |
9 |
High-throughput |
0.536 | High |
|
|
ACTG
Actin, cytoplasmic 2 |
1 |
5 |
High-throughput |
0.536 | High |
|
|
PRDX4
Peroxiredoxin-4 |
1 |
1 |
High-throughput |
0.536 | High |
|
|
TNIP1
TNFAIP3-interacting protein 1 |
1 |
4 |
High-throughput |
0.536 | High |
|
|
SDK2
Protein sidekick-2 |
1 |
7 |
High-throughput |
0.536 | High |
|
|
CCD50
Coiled-coil domain-containing protein 50 |
1 |
1 |
High-throughput |
0.536 | High |
|
|
DAAF1
Dynein axonemal assembly factor 1 |
1 |
2 |
High-throughput |
0.536 | High |
|
|
KIF2C
Kinesin-like protein KIF2C |
1 |
2 |
High-throughput |
0.536 | High |
|
|
E41LB
Band 4.1-like protein 4B |
1 |
12 |
High-throughput |
0.536 | High |
|
|
RNF41
E3 ubiquitin-protein ligase NRDP1 |
1 |
14 |
High-throughput |
0.536 | High |
|
|
ROBO2
Roundabout homolog 2 |
1 |
5 |
High-throughput |
0.536 | High |
|
|
PHOCN
MOB-like protein phocein |
1 |
0 |
High-throughput |
0.518 | High |
|
|
C8AP2
CASP8-associated protein 2 |
1 |
2 |
Small-scale |
0.515 | High |
|
|
NUP42
Nucleoporin NUP42 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
ARK72
Aflatoxin B1 aldehyde reductase member 2 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
TPPP
Tubulin polymerization-promoting protein |
1 |
0 |
High-throughput |
0.513 | High |
|
|
S1PR2
Sphingosine 1-phosphate receptor 2 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
GOG7B
Golgin subfamily A member 7B |
1 |
0 |
High-throughput |
0.513 | High |
|
|
XCT
Cystine/glutamate transporter |
1 |
0 |
High-throughput |
0.513 | High |
|
|
TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 |
1 |
1 |
High-throughput |
0.508 | High |
|
|
ABCA1
Phospholipid-transporting ATPase ABCA1 |
1 |
0 |
Small-scale |
0.504 | High |
|
|
CADH1
Cadherin-1 |
1 |
2 |
Small-scale |
0.501 | High |
|
|
CDC20
Cell division cycle protein 20 homolog |
1 |
1 |
Small-scale |
0.501 | High |
|
|
CH60
60 kDa heat shock protein, mitochondrial |
1 |
0 |
High-throughput |
0.493 | High |
|
|
SDHL
L-serine dehydratase/L-threonine deaminase |
1 |
0 |
High-throughput |
0.493 | High |
|
|
UBC9
SUMO-conjugating enzyme UBC9 |
1 |
2 |
High-throughput |
0.481 | High |
|
|
TLR3
Toll-like receptor 3 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
ATG12
Ubiquitin-like protein ATG12 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
TNFA
Tumor necrosis factor |
1 |
16 |
Small-scale |
0.479 | High |
|
|
NFH
Neurofilament heavy polypeptide |
1 |
8 |
High-throughput |
0.479 | High |
|
|
CDC27
Cell division cycle protein 27 homolog |
1 |
1 |
Small-scale |
0.479 | High |
|
|
KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
TRAF2
TNF receptor-associated factor 2 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
GNDS
Ral guanine nucleotide dissociation stimulator |
1 |
5 |
Small-scale |
0.479 | High |
|
|
SKP2
S-phase kinase-associated protein 2 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
SQSTM
Sequestosome-1 |
1 |
9 |
Small-scale |
0.479 | High |
|
|
CUL3
Cullin-3 |
1 |
6 |
Small-scale |
0.479 | High |
|
|
TRI67
Tripartite motif-containing protein 67 |
1 |
10 |
High-throughput |
0.479 | High |
|
|
AN13A
Ankyrin repeat domain-containing protein 13A |
1 |
10 |
Small-scale |
0.479 | High |
|
|
RYBP
RING1 and YY1-binding protein |
1 |
3 |
Small-scale |
0.479 | High |
|
|
IRF7
Interferon regulatory factor 7 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
CLIP3
CAP-Gly domain-containing linker protein 3 |
1 |
7 |
Small-scale |
0.479 | High |
|
|
XPO5
Exportin-5 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
TNR27
Tumor necrosis factor receptor superfamily member 27 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
DAXX
Death domain-associated protein 6 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
ZRAN1
Ubiquitin thioesterase ZRANB1 |
1 |
14 |
High-throughput |
0.479 | High |
|
|
EDAR
Tumor necrosis factor receptor superfamily member EDAR |
1 |
20 |
Small-scale |
0.479 | High |
|
|
B7ZLH0
FAM22F protein |
1 |
1 |
High-throughput |
0.470 | High |
|
|
Q7KZS0
SUMO-conjugating enzyme UBC9 |
1 |
2 |
High-throughput |
0.470 | High |
|
|
MFN2
Mitofusin-2 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
LRCC1
Leucine-rich repeat and coiled-coil domain-containing protein 1 |
1 |
7 |
High-throughput |
0.457 | High |
|
|
DDX24
ATP-dependent RNA helicase DDX24 |
1 |
4 |
High-throughput |
0.457 | High |
|
|
IGHA1
Immunoglobulin heavy constant alpha 1 |
1 |
3 |
High-throughput |
0.445 | High |
|
|
MOES
Moesin |
1 |
11 |
Small-scale |
0.445 | High |
|
|
BID
BH3-interacting domain death agonist |
1 |
2 |
Small-scale |
0.445 | High |
|
|
RHOA
Transforming protein RhoA |
1 |
9 |
Small-scale |
0.445 | High |
|
|
ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1 |
1 |
11 |
High-throughput |
0.445 | High |
|
|
NTM2F
NUT family member 2F |
1 |
1 |
High-throughput |
0.439 | High |
|
|
PPCE
Prolyl endopeptidase |
1 |
0 |
High-throughput |
0.426 | High |
|
|
P52K
52 kDa repressor of the inhibitor of the protein kinase |
3 |
0 |
High-throughput |
0.347 | High |
|
|
TCEA2
Transcription elongation factor A protein 2 |
2 |
0 |
High-throughput |
0.316 | High |
|
|
ZCH12
Zinc finger CCHC domain-containing protein 12 |
2 |
0 |
High-throughput |
0.316 | High |
|
|
ZMYM5
Zinc finger MYM-type protein 5 |
2 |
0 |
High-throughput |
0.316 | High |
|
|
MBD4
Methyl-CpG-binding domain protein 4 |
1 |
0 |
Small-scale |
0.305 | High |
|
|
KCRU
Creatine kinase U-type, mitochondrial |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
NTF4
Neurotrophin-4 |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
NDNF
Protein NDNF |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
DLDH
Dihydrolipoyl dehydrogenase, mitochondrial |
1 |
0 |
High-throughput |
0.232 | Low |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
