HitPredict

Interactor 1: CYFP2 (Q5SQX6)
Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121)
Gene: Cyfip2

Interactor 2: WASF2 (Q8BH43)
Actin-binding protein WASF2 (Protein WAVE-2) (Wiskott-Aldrich syndrome protein family member 2) (WASP family protein member 2)
Gene: WASF2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32560809
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FragX_IP~WH2
Common GO terms	GO:0031209 - SCAR complex GO:0045202 - synapse
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1253 Mm			1 497
+	Hs
		1390230 CYFP2_HUMAN (1-1253): 0: 2126: 97.97		WASF2_HUMAN (1-497): 3.2e-81: 262: 85.60
+	Hs
		1390226 CYFP2_HUMAN (1-1253): 0: 2126: 97.97		WASF3_HUMAN (1-497): 2.57e-73: 242: 46.72
+	Mm
		1210231 CYFP2_MOUSE (1-1253): 0: 2134: 100.00		WASF1_MOUSE (1-495): 3.88e-61: 211: 41.94
+	Bt
		98944 F1MX60_BOVIN (1-1253): 0: 2129: 99.68		WASF1_BOVIN (1-495): 3.31e-62: 214: 41.76
+	Hs
		1364460 CYFP2_HUMAN (1-1253): 0: 2126: 97.97		WASF1_HUMAN (1-495): 1.06e-62: 215: 41.76
+	Hs
		1272230 CYFP1_HUMAN (1-1252): 0: 2048: 87.55		WASF2_HUMAN (1-497): 3.2e-81: 262: 85.60
+	Hs
		1272225 CYFP1_HUMAN (1-1252): 0: 2048: 87.55		WASF3_HUMAN (1-497): 2.57e-73: 242: 46.72
+	Hs
		1272186 CYFP1_HUMAN (1-1252): 0: 2048: 87.55		WASF1_HUMAN (1-495): 1.06e-62: 215: 41.76
+	Mm
		1274204 CYFP1_MOUSE (1-1252): 0: 2041: 87.31		WASF1_MOUSE (1-495): 3.88e-61: 211: 41.94
+	Dm
		120196 CYFIP_DROME (1-1252): 0: 1908: 66.02		M9PCP4_DROME (1-384): 1.16e-62: 217: 29.98
+	Dm
		99171 CYFIP_DROME (1-1252): 0: 1908: 66.02		F2FB81_DROME (1-384): 5.02e-61: 213: 27.42
+	Dd
		1200685 PIRA_DICDI (7-1224): 0: 1459: 37.72		SCAR_DICDI (25-477): 1.09e-33: 134: 24.62