HitPredict

Interactor 1: F1MX60 (F1MX60)
Cytoplasmic FMR1-interacting protein
Gene: CYFIP2

Interactor 2: WASF1 (Q0IIJ3)
Actin-binding protein WASF1 (Protein WAVE-1) (Wiskott-Aldrich syndrome protein family member 1) (WASP family protein member 1)
Gene: WASF1

Species: Bos taurus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	12181570
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	FragX_IP~WH2
Common GO terms	GO:0005737 - cytoplasm GO:0045202 - synapse
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1252 Bt			1 559
+	Mm
		1210231 CYFP2_MOUSE (1-1252): 0: 2054: 99.68		WASF1_MOUSE (1-559): 5.06e-77: 255: 98.39
+	Hs
		1364460 CYFP2_HUMAN (1-1252): 0: 2046: 97.81		WASF1_HUMAN (1-559): 2.69e-78: 258: 99.46
+	Mm
		1210193 CYFP2_MOUSE (1-1252): 0: 2054: 99.68		WASF2_MOUSE (1-346): 1.51e-63: 217: 45.67
+	Hs
		1272186 CYFP1_HUMAN (1-1251): 0: 1973: 87.39		WASF1_HUMAN (1-559): 2.69e-78: 258: 99.46
+	Hs
		1390226 CYFP2_HUMAN (1-1252): 0: 2046: 97.81		WASF3_HUMAN (1-557): 2.34e-51: 185: 45.34
+	Mm
		1274204 CYFP1_MOUSE (1-1251): 0: 1965: 87.15		WASF1_MOUSE (1-559): 5.06e-77: 255: 98.39
+	Hs
		1390230 CYFP2_HUMAN (1-1252): 0: 2046: 97.81		WASF2_HUMAN (1-541): 3.28e-47: 174: 43.25
+	Hs
		1272225 CYFP1_HUMAN (1-1251): 0: 1973: 87.39		WASF3_HUMAN (1-557): 2.34e-51: 185: 45.34
+	Hs
		1272230 CYFP1_HUMAN (1-1251): 0: 1973: 87.39		WASF2_HUMAN (1-541): 3.28e-47: 174: 43.25
+	Dm
		120196 CYFIP_DROME (1-1251): 0: 1843: 66.09		M9PCP4_DROME (1-542): 1.06e-60: 213: 27.50
+	Mm
		1274212 CYFP1_MOUSE (1-1251): 0: 1965: 87.15		ANR17_MOUSE (117-549): 6.1e-09: 61.3: 11.61
+	Dm
		99171 CYFIP_DROME (1-1251): 0: 1843: 66.09		F2FB81_DROME (226-542): 5.63e-10: 64: 17.21
+	Dd
		1200685 PIRA_DICDI (7-1223): 0: 1405: 37.72		SCAR_DICDI (20-391): 4.54e-29: 121: 18.18