Protein: CYFP1
Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1) (p140sra-1)

Gene: CYFP1, CYFIP1
Organism: Homo sapiens
Interactions: 192
UniProt ID: Q7L576

Gene Ontology (top 5):
GO:0000340 - RNA 7-methylguanosine cap binding
GO:0000902 - cell morphogenesis
GO:0001726 - ruffle
GO:0005576 - extracellular region
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1272227

NCKP1
Nck-associated protein 1

10

6

Small-scale

0.973

High

1272177

ABI1
Abl interactor 1

6

10

Small-scale

0.935

High

1272186

WASF1
Actin-binding protein WASF1

3

12

Small-scale

0.847

High

988476

RAC1
Ras-related C3 botulinum toxin substrate 1

3

17

Small-scale

0.840

High

1272213

ABI2
Abl interactor 2

2

12

High-throughput

0.811

High

1272225

WASF3
Actin-binding protein WASF3

2

13

High-throughput

0.811

High

1272230

WASF2
Actin-binding protein WASF2

2

12

Small-scale

0.798

High

375655

RASK
GTPase KRas

2

3

High-throughput

0.754

High

1272226

BAIP2
BAR/IMD domain-containing adapter protein 2

4

9

High-throughput

0.699

High

222126

NCK2
Cytoplasmic protein NCK2

4

12

High-throughput

0.691

High

1272175

RHG12
Rho GTPase-activating protein 12

3

4

High-throughput

0.650

High

1272185

BRK1
Protein BRICK1

3

3

Small-scale

0.643

High

537401

HSP7C
Heat shock cognate 71 kDa protein

3

1

High-throughput

0.633

High

126667

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

374016

RASN
GTPase NRas

1

3

High-throughput

0.618

High

374708

RASH
GTPase HRas

1

2

High-throughput

0.618

High

581134

RAC2
Ras-related C3 botulinum toxin substrate 2

1

17

High-throughput

0.618

High

910108

RND2
Rho-related GTP-binding protein RhoN

1

18

High-throughput

0.618

High

953525

RAC3
Ras-related C3 botulinum toxin substrate 3

1

17

High-throughput

0.618

High

955323

CDC42
Cell division control protein 42 homolog

1

16

High-throughput

0.618

High

962202

RHOA
Transforming protein RhoA

1

16

High-throughput

0.618

High

978112

RHOB
Rho-related GTP-binding protein RhoB

1

17

High-throughput

0.618

High

1015548

RHOG
Rho-related GTP-binding protein RhoG

1

14

High-throughput

0.618

High

1151751

RHOH
Rho-related GTP-binding protein RhoH

1

16

High-throughput

0.618

High

1270871

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

1272206

RHOJ
Rho-related GTP-binding protein RhoJ

1

17

High-throughput

0.618

High

1272209

RHOF
Rho-related GTP-binding protein RhoF

1

17

High-throughput

0.618

High

459648

PROF1
Profilin-1

2

1

High-throughput

0.611

High

966524

1433G
14-3-3 protein gamma

2

6

High-throughput

0.611

High

1272192

DTBP1
Dysbindin

2

1

High-throughput

0.611

High

1272180

ZN511
Zinc finger protein 511

3

1

High-throughput

0.609

High

1272182

ES8L1
Epidermal growth factor receptor kinase substrate 8-like protein 1

2

13

High-throughput

0.601

High

1138345

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

2

0

High-throughput

0.588

High

1144978

RAB35
Ras-related protein Rab-35

1

0

High-throughput

0.586

High

463609

LYN
Tyrosine-protein kinase Lyn

2

8

High-throughput

0.584

High

862251

YAP1
Transcriptional coactivator YAP1

2

6

High-throughput

0.584

High

1272215

WWOX
WW domain-containing oxidoreductase

2

1

High-throughput

0.584

High

1272221

ZRAN1
Ubiquitin thioesterase ZRANB1

2

1

High-throughput

0.584

High

1272218

ABI3
ABI gene family member 3

1

14

High-throughput

0.575

High

1192192

AMZ1
Archaemetzincin-1

2

1

High-throughput

0.574

High

1272224

CBLC
E3 ubiquitin-protein ligase CBL-C

2

1

High-throughput

0.574

High

1056814

FMR1
Fragile X messenger ribonucleoprotein 1

1

9

Small-scale

0.573

High

396402

ESR1
Estrogen receptor

2

5

High-throughput

0.571

High

1272231

MYO16
Unconventional myosin-XVI

1

3

Small-scale

0.561

High

1272194

RHOV
Rho-related GTP-binding protein RhoV

1

18

High-throughput

0.553

High

900385

FXR2
RNA-binding protein FXR2

1

9

Small-scale

0.552

High

1209314

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

2

High-throughput

0.552

High

594033

NCK1
SH2/SH3 adapter protein NCK1

1

13

High-throughput

0.536

High

729993

1433B
14-3-3 protein beta/alpha

1

6

High-throughput

0.536

High

952922

ACTB
Actin, cytoplasmic 1

1

5

High-throughput

0.536

High

990407

1433Z
14-3-3 protein zeta/delta

1

6

High-throughput

0.536

High

993228

ACTG
Actin, cytoplasmic 2

1

5

High-throughput

0.536

High

1049477

1433F
14-3-3 protein eta

1

6

High-throughput

0.536

High

1272195

MARK4
MAP/microtubule affinity-regulating kinase 4

1

1

High-throughput

0.536

High

1272222

LIMA1
LIM domain and actin-binding protein 1

1

1

High-throughput

0.536

High

218375

TGON2
Trans-Golgi network integral membrane protein 2

2

4

High-throughput

0.521

High

983518

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

0

High-throughput

0.518

High

451191

NFL
Neurofilament light polypeptide

1

3

High-throughput

0.515

High

904873

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.515

High

1272170

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

3

High-throughput

0.515

High

447155

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

551124

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.513

High

563974

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

844811

EAA1
Excitatory amino acid transporter 1

1

0

High-throughput

0.513

High

1272198

ARX
Homeobox protein ARX

1

0

High-throughput

0.513

High

786695

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

2

Small-scale

0.508

High

1238067

CGB2
Choriogonadotropin subunit beta variant 2

2

1

High-throughput

0.504

High

127121

APBB1
Amyloid beta precursor protein binding family B member 1

1

1

High-throughput

0.501

High

280687

PR40A
Pre-mRNA-processing factor 40 homolog A

1

7

High-throughput

0.501

High

445569

IF4E
Eukaryotic translation initiation factor 4E

1

1

Small-scale

0.501

High

868033

SCTR
Secretin receptor

1

2

High-throughput

0.494

High

830967

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

167300

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.493

High

246001

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.493

High

369692

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.493

High

1192044

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

2

High-throughput

0.489

High

1258635

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

1

High-throughput

0.489

High

1272216

NHSL3
NHS-like protein 3

1

4

High-throughput

0.489

High

1272229

KC1G3
Casein kinase I isoform gamma-3

1

2

High-throughput

0.489

High

258386

GAS7
Growth arrest-specific protein 7

1

4

High-throughput

0.481

High

132125

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

1

High-throughput

0.479

High

242104

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

345995

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

363483

EGFR
Epidermal growth factor receptor

1

9

High-throughput

0.479

High

372400

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

404156

GCR
Glucocorticoid receptor

1

5

High-throughput

0.479

High

412152

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.479

High

463137

YES
Tyrosine-protein kinase Yes

1

9

High-throughput

0.479

High

463995

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

10

High-throughput

0.479

High

520159

ANDR
Androgen receptor

1

5

High-throughput

0.479

High

540522

LAMP1
Lysosome-associated membrane glycoprotein 1

1

1

High-throughput

0.479

High

557357

SRC
Proto-oncogene tyrosine-protein kinase Src

1

8

High-throughput

0.479

High

582853

EZRI
Ezrin

1

4

High-throughput

0.479

High

614702

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

2

High-throughput

0.479

High

642942

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

1

High-throughput

0.479

High

710329

EPHA2
Ephrin type-A receptor 2

1

9

High-throughput

0.479

High

710851

EPHB2
Ephrin type-B receptor 2

1

9

High-throughput

0.479

High

731417

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

761249

RYK
Tyrosine-protein kinase RYK

1

10

Small-scale

0.479

High

764861

CTNB1
Catenin beta-1

1

3

High-throughput

0.479

High

767065

PTN7
Tyrosine-protein phosphatase non-receptor type 7

1

4

High-throughput

0.479

High

840888

TEC
Tyrosine-protein kinase Tec

1

8

High-throughput

0.479

High

845696

MUC18
Cell surface glycoprotein MUC18

1

1

High-throughput

0.479

High

876912

KC1A
Casein kinase I isoform alpha

1

1

High-throughput

0.479

High

896568

VASP
Vasodilator-stimulated phosphoprotein

1

4

High-throughput

0.479

High

899998

FXR1
RNA-binding protein FXR1

1

9

Small-scale

0.479

High

920065

PLK1
Serine/threonine-protein kinase PLK1

1

2

High-throughput

0.479

High

970700

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

975102

ARF6
ADP-ribosylation factor 6

1

2

High-throughput

0.479

High

995662

ACTC
Actin, alpha cardiac muscle 1

1

5

High-throughput

0.479

High

1040839

MECOM
Histone-lysine N-methyltransferase MECOM

1

1

High-throughput

0.479

High

1113511

CUL3
Cullin-3

1

2

High-throughput

0.479

High

1147358

EPHA7
Ephrin type-A receptor 7

1

7

High-throughput

0.479

High

1155494

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

1156532

CCDC6
Coiled-coil domain-containing protein 6

1

3

High-throughput

0.479

High

1211742

UBX11
UBX domain-containing protein 11

1

1

High-throughput

0.479

High

1226945

A16L1
Autophagy-related protein 16-1

1

3

High-throughput

0.479

High

1272174

CUL9
Cullin-9

1

1

High-throughput

0.479

High

1272187

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

1272189

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.479

High

1272199

RUFY1
RUN and FYVE domain-containing protein 1

1

2

High-throughput

0.479

High

1272201

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.479

High

1272204

WWTR1
WW domain-containing transcription regulator protein 1

1

4

High-throughput

0.479

High

1272208

PRD16
Histone-lysine N-methyltransferase PRDM16

1

1

High-throughput

0.479

High

1272223

FKBPL
FK506-binding protein-like

1

1

High-throughput

0.479

High

125515

LEG9
Galectin-9

1

0

High-throughput

0.458

High

129210

MEN1
Menin

1

0

High-throughput

0.458

High

567436

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

620437

NUCL
Nucleolin

1

0

Small-scale

0.458

High

764381

CTNA1
Catenin alpha-1

1

0

Small-scale

0.458

High

791486

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

927042

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

986524

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.458

High

1098045

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.458

High

1194177

LARP7
La-related protein 7

1

0

High-throughput

0.458

High

1229544

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1238431

ZN746
Zinc finger protein 746

1

0

High-throughput

0.458

High

1246856

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

1272178

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

1272181

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1272191

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.458

High

1272196

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1272203

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

0

High-throughput

0.458

High

1272210

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

1272211

ANLN
Anillin

1

0

High-throughput

0.458

High

1272214

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

163793

TCRG1
Transcription elongation regulator 1

1

5

High-throughput

0.457

High

1256814

NYAP1
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1

1

10

Small-scale

0.457

High

1272217

NYAP2
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2

1

9

Small-scale

0.457

High

1110483

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

5

High-throughput

0.445

High

106168

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

589008

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

695795

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

768508

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

898244

R144A
E3 ubiquitin-protein ligase RNF144A

1

1

Small-scale

0.437

High

928483

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.437

High

1004757

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

1100050

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.437

High

1114913

CUL4A
Cullin-4A

1

2

High-throughput

0.437

High

1149918

TERF2
Telomeric repeat-binding factor 2

1

1

High-throughput

0.437

High

1254377

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1272176

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.437

High

1272188

ESR2
Estrogen receptor beta

1

5

High-throughput

0.437

High

1272190

LHX4
LIM/homeobox protein Lhx4

1

2

High-throughput

0.437

High

1272207

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

1272219

PCD10
Protocadherin-10

1

1

Small-scale

0.437

High

1272220

HECW2
E3 ubiquitin-protein ligase HECW2

1

1

High-throughput

0.437

High

1272184

CE192
Centrosomal protein of 192 kDa

1

0

High-throughput

0.426

High

1272197

CEP63
Centrosomal protein of 63 kDa

1

0

High-throughput

0.426

High

62547

S35F4
Solute carrier family 35 member F4

1

1

High-throughput

0.407

High

1205196

NHSL2
NHS-like protein 2

1

2

High-throughput

0.407

High

893705

MEOX1
Homeobox protein MOX-1

1

0

High-throughput

0.282

High

1206392

EFHC2
EF-hand domain-containing family member C2

1

0

High-throughput

0.282

High

1272173

RFX6
DNA-binding protein RFX6

1

0

High-throughput

0.282

High

1272200

PCGF1
Polycomb group RING finger protein 1

1

0

Small-scale

0.279

Low

1272205

CAD23
Cadherin-23

1

0

High-throughput

0.279

Low

301511

WFS1
Wolframin

1

0

High-throughput

0.268

Low

272962

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

0

High-throughput

0.249

Low

1041673

TNAP2
Tumor necrosis factor alpha-induced protein 2

1

0

Small-scale

0.249

Low

1135487

T132D
Transmembrane protein 132D

1

0

Small-scale

0.249

Low

1153553

MLF2
Myeloid leukemia factor 2

1

0

High-throughput

0.249

Low

1241892

FBX42
F-box only protein 42

1

0

High-throughput

0.249

Low

1258334

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.249

Low

1272169

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1272172

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1272179

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.249

Low

1272183

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.249

Low

1272212

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

1272228

INSI2
Insulin-induced gene 2 protein

1

0

High-throughput

0.249

Low

1272171

SL9B2
Sodium/hydrogen exchanger 9B2

1

0

High-throughput

0.232

Low

1272193

S41A3
Solute carrier family 41 member 3

1

0

High-throughput

0.232

Low

1272202

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025