Interactor 1: DPS1 (Q5T2R2)
All trans-polyprenyl-diphosphate synthase PDSS1 (All-trans-decaprenyl-diphosphate synthase subunit 1) (EC 2.5.1.91) (Decaprenyl pyrophosphate synthase subunit 1) (Decaprenyl-diphosphate synthase subunit 1) (Solanesyl-diphosphate synthase subunit 1) (Trans-prenyltransferase 1) (TPT 1)
Gene: PDSS1

Interactor 2: DLP1 (Q86YH6)
All trans-polyprenyl-diphosphate synthase PDSS2 (All-trans-decaprenyl-diphosphate synthase subunit 2) (EC 2.5.1.91) (Candidate tumor suppressor protein) (Decaprenyl pyrophosphate synthase subunit 2) (Decaprenyl-diphosphate synthase subunit 2) (Solanesyl-diphosphate synthase subunit 2)
Gene: PDSS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 38334954, 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains polyprenyl_synt~polyprenyl_synt
Common GO terms GO:0004659 - prenyltransferase activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006744 - ubiquinone biosynthetic process
GO:0008299 - isoprenoid biosynthetic process
and 6 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 415
Hs

1 399
+ Hs
+ Hs
+ At
+ Hs
+ Ec
+ Sp
+ Sp
+ Sp
+ Sp
+ Hs
+ Hp
+ Sc
+ Ec

Service provided by Combinatics, Japan

Last updated: 11Aug2025