HitPredict

Interactor 1: NUDC3 (Q8IVD9)
NudC domain-containing protein 3
Gene: NUDCD3

Interactor 2: KLDC2 (Q9Y2U9)
Kelch domain-containing protein 2 (Hepatocellular carcinoma-associated antigen 33) (Host cell factor homolog LCP) (Host cell factor-like protein 1) (HCLP-1)
Gene: KLHDC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	28514442, 33961781, 25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 361 Hs			1 406
+	Hs
		299523 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLH18_HUMAN (87-405): 5.72e-60: 206: 15.85
+	Hs
		1217464 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLH20_HUMAN (165-406): 2.16e-53: 189: 13.17
+	Hs
		1217446 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLH28_HUMAN (87-404): 1.39e-52: 186: 13.85
+	Hs
		1217455 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLHL3_HUMAN (165-400): 3.41e-45: 166: 14.41
+	Hs
		848248 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		HCFC1_HUMAN (1-302): 6.46e-41: 157: 17.43
+	Hs
		1161736 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLD10_HUMAN (139-399): 2.36e-38: 145: 17.84
+	Hs
		985637 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		Q05C05_HUMAN (5-251): 2.38e-36: 141: 17.78
+	Hs
		1217468 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		HCFC2_HUMAN (5-251): 9.3e-34: 135: 17.22
+	Hs
		1217431 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLHL4_HUMAN (228-405): 1.02e-31: 129: 15.17
+	Hs
		1049257 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KEAP1_HUMAN (226-406): 5.71e-30: 123: 15.76
+	Hs
		1217428 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLDC3_HUMAN (5-195): 2.91e-29: 119: 16.58
+	Hs
		1217438 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLHL1_HUMAN (4-154): 7.35e-26: 111: 11.92
+	Hs
		1120783 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLH12_HUMAN (6-156): 1.27e-25: 110: 16.56
+	Hs
		1217405 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLDC1_HUMAN (217-405): 7.57e-24: 104: 12.56
+	Hs
		1159387 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		FBX42_HUMAN (212-366): 7.52e-22: 99.9: 25.00
+	Hs
		1217450 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLHL9_HUMAN (265-402): 2.48e-13: 73.6: 15.07
+	Hs
		1217452 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLH13_HUMAN (280-402): 3.05e-13: 73.2: 13.74
+	Hs
		1377063 NUDC_HUMAN (7-343): 2.07e-102: 306: 27.38		HCFC2_HUMAN (5-251): 9.3e-34: 135: 17.22
+	Hs
		1237058 NUDC_HUMAN (7-343): 2.07e-102: 306: 27.38		KLDC1_HUMAN (217-405): 7.57e-24: 104: 12.56
+	Hs
		1159402 NUDC2_HUMAN (191-344): 9.87e-31: 116: 19.11		FBX42_HUMAN (212-366): 7.52e-22: 99.9: 25.00