HitPredict

Interactor 1: FHI2A (Q5W0V3)
FHF complex subunit HOOK interacting protein 2A (FHIP2A)
Gene: FHIP2A

Interactor 2: HOOK3 (Q86VS8)
Protein Hook homolog 3 (h-hook3) (hHK3)
Gene: HOOK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.80	0.694

Property	Details
Experiments	28718761, 34882091
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DUF5917~HOOK, HOOK~KELAA, HOOK~RAI16-like
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 765 Hs			1 718
+	Hs
		1219952 FHI2A_HUMAN (1-765): 0: 1154: 100.00		HOOK2_HUMAN (6-718): 4.81e-39: 156: 46.37
+	Hs
		1290234 FHI2B_HUMAN (1-759): 0: 1099: 51.05		HOOK3_HUMAN (1-718): 7.61e-58: 211: 100.00
+	Hs
		1290240 FHI2B_HUMAN (1-759): 0: 1099: 51.05		HOOK2_HUMAN (6-718): 4.81e-39: 156: 46.37
+	Hs
		1219963 FHI2A_HUMAN (1-765): 0: 1154: 100.00		HOOK1_HUMAN (196-707): 6.37e-12: 71.2: 10.51
+	Hs
		1290245 FHI2B_HUMAN (1-759): 0: 1099: 51.05		HOOK1_HUMAN (196-707): 6.37e-12: 71.2: 10.51
+	Hs
		1053458 FHI1A_HUMAN (235-613): 3.42e-85: 293: 20.67		HOOK3_HUMAN (1-718): 7.61e-58: 211: 100.00
+	Hs
		1291547 FHI1B_HUMAN (249-577): 4.81e-80: 278: 22.29		HOOK3_HUMAN (1-718): 7.61e-58: 211: 100.00
+	Hs
		1053459 FHI1A_HUMAN (235-613): 3.42e-85: 293: 20.67		HOOK2_HUMAN (6-718): 4.81e-39: 156: 46.37
+	Hs
		1328725 FHI1B_HUMAN (249-577): 4.81e-80: 278: 22.29		HOOK2_HUMAN (6-718): 4.81e-39: 156: 46.37
+	Hs
		773226 FHI1B_HUMAN (249-577): 4.81e-80: 278: 22.29		MYH10_HUMAN (195-718): 3.82e-20: 98.2: 10.76
+	Hs
		1053463 FHI1A_HUMAN (235-613): 3.42e-85: 293: 20.67		HOOK1_HUMAN (196-707): 6.37e-12: 71.2: 10.51
+	Hs
		1328732 FHI1B_HUMAN (249-577): 4.81e-80: 278: 22.29		HOOK1_HUMAN (196-707): 6.37e-12: 71.2: 10.51
+	Hs
		772905 FHI1B_HUMAN (249-577): 4.81e-80: 278: 22.29		MYH9_HUMAN (401-717): 2.24e-10: 66.6: 11.67