Interactor 1: HOOK3 (Q86VS8)
Protein Hook homolog 3 (h-hook3) (hHK3)
Gene: HOOK3
Interactor 2: FHI1B (Q8N612)
FHF complex subunit HOOK-interacting protein 1B (FHIP1B) (FTS- and Hook-interacting protein) (FHIP)
Gene: FHIP1B
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.968 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32073997, 34882091, 28514442, 28718761, 33961781, 18799622, unassigned3799 |
| Identification Methods | two hybrid, proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DUF5917~HOOK, HOOK~KELAA, HOOK~RAI16-like |
| Common GO terms | GO:0007032 - endosome organization GO:0007040 - lysosome organization GO:0008333 - endosome to lysosome transport GO:0015031 - protein transport GO:0045022 - early endosome to late endosome transport and 2 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
