HitPredict

Interactor 1: CCAR1 (Q8IX12)
Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain)
Gene: CCAR1

Interactor 2: NEMO (Q9Y6K9)
NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28514442, 14743216
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006915 - apoptotic process
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1150 Hs			1 419
+	Hs
		1220151 CCAR1_HUMAN (1-1150): 0: 720: 100.00		SCAPE_HUMAN (25-345): 4.15e-29: 122: 16.91
+	Hs
		725276 MYH10_HUMAN (407-1150): 2.28e-24: 113: 9.32		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Hs
		502925 MYH3_HUMAN (390-1134): 4.04e-17: 89.7: 11.04		OPTN_HUMAN (67-418): 2.78e-38: 147: 27.25
+	Hs
		1078856 MYH14_HUMAN (590-1145): 3.37e-20: 99.7: 14.01		ITSN1_HUMAN (24-403): 1.07e-30: 127: 12.15
+	Hs
		724687 MYH10_HUMAN (407-1150): 2.28e-24: 113: 9.32		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		725095 MYH10_HUMAN (407-1150): 2.28e-24: 113: 9.32		MYH10_HUMAN (27-387): 1.16e-10: 65.8: 14.09
+	Hs
		725097 MYH10_HUMAN (407-1150): 2.28e-24: 113: 9.32		MYH11_HUMAN (13-392): 2.7e-09: 61.5: 13.42
+	Dm
		1001870 Q0KI67_DROME (578-1143): 1.85e-14: 80.8: 16.17		Q0KI67_DROME (48-381): 2.76e-19: 92.7: 15.83
+	Hs
		724895 MYH14_HUMAN (590-1145): 3.37e-20: 99.7: 14.01		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		725189 MYH14_HUMAN (590-1145): 3.37e-20: 99.7: 14.01		MYH10_HUMAN (27-387): 1.16e-10: 65.8: 14.09
+	Hs
		528435 MYH8_HUMAN (409-1148): 1.18e-21: 104: 10.01		MYH4_HUMAN (21-393): 8.88e-09: 60: 13.44
+	Dm
		1303379 MYSN_DROME (525-1141): 6.5e-19: 95.5: 11.18		MYSN_DROME (48-367): 2.18e-10: 65: 19.89
+	Hs
		522657 MYH4_HUMAN (589-1150): 5.13e-18: 92.4: 11.95		MYH7_HUMAN (26-376): 1.58e-09: 62.3: 13.24
+	Hs
		502901 MYH3_HUMAN (390-1134): 4.04e-17: 89.7: 11.04		MYH6_HUMAN (4-395): 1.4e-09: 62.3: 11.48
+	Hs
		528432 MYH13_HUMAN (420-1149): 1.29e-16: 87.8: 8.49		MYH8_HUMAN (22-392): 1.71e-09: 62.3: 11.87
+	Hs
		502933 MYH3_HUMAN (390-1134): 4.04e-17: 89.7: 11.04		MYH4_HUMAN (21-393): 8.88e-09: 60: 13.44
+	Mm
		93570 MYH9_MOUSE (418-1022): 4.07e-16: 86.3: 8.60		DESP_MOUSE (49-376): 9.41e-09: 60: 17.60
+	Hs
		724686 MYH9_HUMAN (710-1150): 5.15e-13: 76.2: 9.03		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93