Protein: RN170
E3 ubiquitin-protein ligase RNF170 (EC 2.3.2.27) (Putative LAG1-interacting protein) (RING finger protein 170) (RING-type E3 ubiquitin transferase RNF170)

Gene: RN170, RNF170
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q96K19

Gene Ontology (top 5):
GO:0005789 - endoplasmic reticulum membrane
GO:0007628 - adult walking behavior
GO:0008270 - zinc ion binding
GO:0009266 - response to temperature stimulus
GO:0010467 - gene expression

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

982288

UB2D2
Ubiquitin-conjugating enzyme E2 D2

2

1

Small-scale

0.778

High

1218744

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

2

High-throughput

0.698

High

321333

ERLN2
Erlin-2

4

3

Small-scale

0.694

High

283335

ERLN1
Erlin-1

3

3

High-throughput

0.667

High

1395621

TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1

2

0

Small-scale

0.660

High

1291461

RETR3
Reticulophagy regulator 3

3

0

High-throughput

0.638

High

1348040

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

3

0

High-throughput

0.620

High

1395625

P2Y12
P2Y purinoceptor 12

3

2

High-throughput

0.609

High

1395627

RDH14
Retinol dehydrogenase 14

2

0

High-throughput

0.602

High

934267

BI1
Bax inhibitor 1

2

0

High-throughput

0.585

High

1129021

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

2

2

Small-scale

0.584

High

72876

HACD1
Very-long-chain

2

0

High-throughput

0.580

High

1313637

PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

2

0

High-throughput

0.580

High

996005

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

2

High-throughput

0.579

High

226859

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

2

2

High-throughput

0.553

High

1389488

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

2

High-throughput

0.553

High

954881

PSA6
Proteasome subunit alpha type-6

1

0

High-throughput

0.549

High

191230

TLR3
Toll-like receptor 3

1

0

Small-scale

0.537

High

1395632

UBQL2
Ubiquilin-2

1

0

High-throughput

0.517

High

230656

PRIC3
Prickle planar cell polarity protein 3

1

0

High-throughput

0.513

High

1085459

SRBP2
Sterol regulatory element-binding protein 2

1

0

High-throughput

0.513

High

1395628

AT132
Polyamine-transporting ATPase 13A2

1

0

High-throughput

0.513

High

907049

CCR6
C-C chemokine receptor type 6

1

1

High-throughput

0.489

High

1101633

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

1

High-throughput

0.489

High

1395616

RN170
E3 ubiquitin-protein ligase RNF170

1

0

Small-scale

0.480

High

1128454

ITPR3
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3

1

2

High-throughput

0.479

High

1391907

RN185
E3 ubiquitin-protein ligase RNF185

1

2

High-throughput

0.479

High

445048

S10A9
Protein S100-A9

1

0

High-throughput

0.458

High

1199237

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

0

High-throughput

0.458

High

1249123

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1395098

TMX3
Protein disulfide-isomerase TMX3

1

0

High-throughput

0.458

High

1395633

AMFR
E3 ubiquitin-protein ligase AMFR

1

0

High-throughput

0.458

High

1395634

TMCO1
Calcium load-activated calcium channel

1

0

High-throughput

0.458

High

1103571

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

2

0

High-throughput

0.328

High

1234000

ASPH2
Aspartate beta-hydroxylase domain-containing protein 2

2

0

High-throughput

0.328

High

1351779

ST7L
Suppressor of tumorigenicity 7 protein-like

2

0

High-throughput

0.328

High

1395629

ABCBA
ATP-binding cassette sub-family B member 10, mitochondrial

2

0

High-throughput

0.328

High

1395630

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

2

0

High-throughput

0.328

High

1366179

LPAR1
Lysophosphatidic acid receptor 1

2

0

High-throughput

0.318

High

139293

UPK2
Uroplakin-2

2

0

High-throughput

0.316

High

1133223

STAR3
StAR-related lipid transfer protein 3

2

0

High-throughput

0.316

High

1203124

SGMR2
Sigma intracellular receptor 2

2

0

High-throughput

0.316

High

1210093

SNP47
Synaptosomal-associated protein 47

2

0

High-throughput

0.316

High

1395617

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

2

0

High-throughput

0.316

High

1395620

TM109
Voltage-gated monoatomic cation channel TMEM109

2

0

High-throughput

0.316

High

772960

MYH9
Myosin-9

1

0

High-throughput

0.279

Low

868011

GLR
Glucagon receptor

1

0

High-throughput

0.279

Low

902943

DUS3
Dual specificity protein phosphatase 3

1

0

High-throughput

0.279

Low

956226

RAB4B
Ras-related protein Rab-4B

1

0

High-throughput

0.279

Low

1364106

TM9S4
Transmembrane 9 superfamily member 4

1

0

High-throughput

0.279

Low

1395623

PAR6B
Partitioning defective 6 homolog beta

1

0

High-throughput

0.279

Low

1395626

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.279

Low

296862

GABR2
Gamma-aminobutyric acid type B receptor subunit 2

1

0

High-throughput

0.269

Low

1395624

FXYD6
FXYD domain-containing ion transport regulator 6

1

0

High-throughput

0.251

Low

218633

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

877371

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.249

Low

958693

CSN2
COP9 signalosome complex subunit 2

1

0

High-throughput

0.249

Low

1143774

PON2
Serum paraoxonase/arylesterase 2

1

0

High-throughput

0.249

Low

1278665

CF120
UPF0669 protein C6orf120

1

0

High-throughput

0.249

Low

1334252

ATAD1
Outer mitochondrial transmembrane helix translocase

1

0

High-throughput

0.249

Low

1334784

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.249

Low

1395631

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

0

High-throughput

0.249

Low

870288

S6A12
Sodium- and chloride-dependent betaine transporter

1

0

High-throughput

0.232

Low

1395618

B3A4
Anion exchange protein 4

1

0

High-throughput

0.232

Low

1395619

S26A8
Testis anion transporter 1

1

0

High-throughput

0.232

Low

1395622

S12A9
Solute carrier family 12 member 9

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025