HitPredict

Interactor 1: NR0B1 (Q61066)
Nuclear receptor subfamily 0 group B member 1 (Nuclear receptor DAX-1)
Gene: NR0B1

Interactor 2: RIF1 (Q6PR54)
Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1)
Gene: RIF1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	20362541, 17093407
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 472 Mm			1 2419
+	Mm
		1222844 ERR2_MOUSE (77-472): 5.66e-78: 251: 16.67		RIF1_MOUSE (1-2419): 0: 1666: 100.00
+	Hs
		396294 ESR1_HUMAN (72-471): 6.42e-72: 240: 14.78		RIF1_HUMAN (1-2419): 0: 1570: 67.66
+	Hs
		773127 NR2C2_HUMAN (183-471): 9.48e-67: 226: 23.59		MYH10_HUMAN (986-2012): 3.46e-34: 147: 10.94
+	Hs
		396358 ESR1_HUMAN (72-471): 6.42e-72: 240: 14.78		ANR11_HUMAN (951-2273): 4.84e-29: 130: 9.33
+	Hs
		834038 HNF4A_HUMAN (114-470): 5.61e-90: 283: 18.55		MINT_HUMAN (954-2414): 9.67e-16: 86.5: 6.80
+	Hs
		1247960 ESR2_HUMAN (75-472): 3.19e-71: 236: 14.90		ANR11_HUMAN (951-2273): 4.84e-29: 130: 9.33
+	Hs
		396114 ESR1_HUMAN (72-471): 6.42e-72: 240: 14.78		MDC1_HUMAN (935-2415): 3.33e-27: 124: 7.41
+	Hs
		1129670 ESR2_HUMAN (75-472): 3.19e-71: 236: 14.90		MDC1_HUMAN (935-2415): 3.33e-27: 124: 7.41
+	Hs
		1275896 ESR2_HUMAN (75-472): 3.19e-71: 236: 14.90		TICRR_HUMAN (1004-2370): 5.41e-27: 123: 9.59
+	Hs
		833969 HNF4A_HUMAN (114-470): 5.61e-90: 283: 18.55		NIPBL_HUMAN (1421-2211): 2.09e-11: 72.3: 11.63
+	Hs
		396417 ESR1_HUMAN (72-471): 6.42e-72: 240: 14.78		RBBP6_HUMAN (1488-2145): 1.72e-16: 88.9: 11.60
+	Hs
		396770 ESR1_HUMAN (72-471): 6.42e-72: 240: 14.78		MINT_HUMAN (954-2414): 9.67e-16: 86.5: 6.80
+	Hs
		1279878 ESR2_HUMAN (75-472): 3.19e-71: 236: 14.90		RBBP6_HUMAN (1488-2145): 1.72e-16: 88.9: 11.60
+	Hs
		1338694 ESR2_HUMAN (75-472): 3.19e-71: 236: 14.90		BD1L1_HUMAN (974-2043): 2.44e-16: 88.5: 10.87
+	Hs
		1367725 ESR2_HUMAN (75-472): 3.19e-71: 236: 14.90		PCLO_HUMAN (918-2419): 5.5e-16: 87.3: 8.44
+	Hs
		396612 ESR1_HUMAN (72-471): 6.42e-72: 240: 14.78		TITIN_HUMAN (1305-2388): 7.55e-14: 80.4: 8.62
+	Hs
		1361882 ESR2_HUMAN (75-472): 3.19e-71: 236: 14.90		TITIN_HUMAN (1305-2388): 7.55e-14: 80.4: 8.62
+	Hs
		396322 ESR1_HUMAN (72-471): 6.42e-72: 240: 14.78		NIPBL_HUMAN (1421-2211): 2.09e-11: 72.3: 11.63
+	Hs
		395513 ESR1_HUMAN (72-471): 6.42e-72: 240: 14.78		APC_HUMAN (944-2181): 5.26e-11: 71: 8.83
+	Hs
		1235663 ESR2_HUMAN (75-472): 3.19e-71: 236: 14.90		NIPBL_HUMAN (1421-2211): 2.09e-11: 72.3: 11.63