HitPredict

Interactor 1: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Interactor 2: DCAF1 (Q9Y4B6)
DDB1- and CUL4-associated factor 1 (HIV-1 Vpr-binding protein) (VprBP) (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) (Vpr-interacting protein)
Gene: DCAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19596235
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1834 Hs			1 1507
+	Hs
		903358 SLX4_HUMAN (1-1834): 0: 1486: 100.00		WDR5_HUMAN (923-1244): 5.84e-46: 171: 13.02
+	Hs
		197053 SLX4_HUMAN (1-1834): 0: 1486: 100.00		PRP4_HUMAN (1178-1389): 5.63e-30: 128: 11.74
+	Hs
		929555 SLX4_HUMAN (1-1834): 0: 1486: 100.00		RACK1_HUMAN (1049-1209): 4.28e-28: 118: 10.86
+	Mm
		903669 KMT2C_MOUSE (886-1764): 1.24e-21: 105: 10.35		WDR5_MOUSE (923-1244): 5.84e-46: 171: 13.02
+	Hs
		903405 CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57		WDR5_HUMAN (923-1244): 5.84e-46: 171: 13.02
+	Hs
		152622 KMT2D_HUMAN (889-1742): 5.87e-09: 63.6: 9.85		WDR5_HUMAN (923-1244): 5.84e-46: 171: 13.02
+	Hs
		1281391 PRR36_HUMAN (1119-1781): 3.16e-14: 80.9: 8.56		FBXW7_HUMAN (1039-1242): 6.77e-37: 152: 9.64
+	Hs
		801423 KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79		NLE1_HUMAN (972-1164): 2.95e-28: 122: 14.43
+	Hs
		801070 KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79		RACK1_HUMAN (1049-1209): 4.28e-28: 118: 10.86
+	Hs
		152678 KMT2D_HUMAN (889-1742): 5.87e-09: 63.6: 9.85		FBXW7_HUMAN (1039-1242): 6.77e-37: 152: 9.64
+	Hs
		929460 MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54		RACK1_HUMAN (1049-1209): 4.28e-28: 118: 10.86
+	Hs
		152663 KMT2D_HUMAN (889-1742): 5.87e-09: 63.6: 9.85		WDR5B_HUMAN (1207-1379): 3.77e-28: 119: 10.33