HitPredict

Interactor 1: GRID1 (Q62640)
Glutamate receptor ionotropic, delta-1 (GluD1) (GluR delta-1 subunit)
Gene: GRID1

Interactor 2: GRID1 (Q62640)
Glutamate receptor ionotropic, delta-1 (GluD1) (GluR delta-1 subunit)
Gene: GRID1

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.49 1.00 0.701

The method score is based on:

Property Details
Experiments 31925409
Identification Methods 3D electron microscopy, protein cross-linking with a bifunctional reagent, comigration in sds page
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan-Glu_bd~Lig_chan-Glu_bd
Common GO terms GO:0004971 - AMPA glutamate receptor activity
GO:0005886 - plasma membrane
GO:0007200 - phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0016917 - GABA receptor activity
GO:0031914 - negative regulation of synaptic plasticity
and 16 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

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Last updated: 11Aug2025