HitPredict

Interactor 1: XRN1 (Q8IZH2)
5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog)
Gene: XRN1

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1706 Hs			1 523
+	Hs
		1031389 XRN1_HUMAN (1-1706): 0: 2785: 100.00		PABP4_HUMAN (3-149): 2.52e-27: 118: 18.83
+	Hs
		1224398 XRN1_HUMAN (1-1706): 0: 2785: 100.00		RBM4B_HUMAN (83-190): 4.07e-09: 60.5: 33.04
+	Hs
		1224403 XRN1_HUMAN (1-1706): 0: 2785: 100.00		RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14
+	Sc
		376636 XRN1_YEAST (1-1267): 0: 1403: 32.34		PABP_YEAST (4-373): 1.42e-48: 178: 14.85
+	Hs
		1263532 XRN2_HUMAN (1-700): 0: 978: 34.46		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		1222313 XRN2_HUMAN (1-700): 0: 978: 34.46		RAVR1_HUMAN (84-234): 5.69e-14: 76.4: 23.35
+	Hs
		1077492 XRN2_HUMAN (1-700): 0: 978: 34.46		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Sc
		376906 XRN2_YEAST (349-719): 4.07e-110: 377: 24.55		PABP_YEAST (4-373): 1.42e-48: 178: 14.85