HitPredict

Interactor 1: DX39A (O00148)
ATP-dependent RNA helicase DDX39A (EC 3.6.4.13) (DEAD box protein 39) (Nuclear RNA helicase URH49)
Gene: DDX39A

Interactor 2: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0045824 - negative regulation of innate immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 427 Hs			1 248
+	Hs
		608468 DDX5_HUMAN (6-420): 3.96e-130: 390: 24.82		1433S_HUMAN (1-248): 3.5e-158: 440: 100.00
+	Hs
		730574 DX39B_HUMAN (1-427): 9.78e-133: 390: 89.49		1433S_HUMAN (1-248): 3.5e-158: 440: 100.00
+	At
		840461 RH20_ARATH (20-420): 6.03e-137: 403: 25.80		14333_ARATH (3-247): 2.64e-144: 405: 58.30
+	Hs
		971507 DX39B_HUMAN (1-427): 9.78e-133: 390: 89.49		1433E_HUMAN (2-246): 4.43e-146: 410: 60.41
+	Hs
		807344 IF4A3_HUMAN (25-420): 3.88e-123: 365: 32.83		1433E_HUMAN (2-246): 4.43e-146: 410: 60.41
+	Hs
		807361 IF4A3_HUMAN (25-420): 3.88e-123: 365: 32.83		1433Z_HUMAN (1-242): 8.34e-142: 398: 70.66
+	Hs
		684093 DDX6_HUMAN (29-425): 2.51e-75: 244: 36.59		1433S_HUMAN (1-248): 3.5e-158: 440: 100.00
+	Hs
		608527 DDX5_HUMAN (6-420): 3.96e-130: 390: 24.82		1433G_HUMAN (1-242): 1.87e-98: 289: 65.16
+	Hs
		966296 DX39B_HUMAN (1-427): 9.78e-133: 390: 89.49		1433G_HUMAN (1-242): 1.87e-98: 289: 65.16
+	Hs
		690797 IF4A3_HUMAN (25-420): 3.88e-123: 365: 32.83		1433T_HUMAN (1-238): 1e-107: 312: 71.85
+	Mm
		999292 DX39B_MOUSE (1-427): 8.67e-133: 390: 89.95		1433F_MOUSE (2-242): 1.73e-96: 284: 64.20
+	Mm
		932540 DDX6_MOUSE (29-425): 1.35e-75: 245: 36.59		1433E_MOUSE (2-246): 4.43e-146: 410: 60.41
+	Hs
		684164 DDX6_HUMAN (29-425): 2.51e-75: 244: 36.59		1433E_HUMAN (2-246): 4.43e-146: 410: 60.41
+	Hs
		807340 IF4A3_HUMAN (25-420): 3.88e-123: 365: 32.83		1433G_HUMAN (1-242): 1.87e-98: 289: 65.16
+	At
		834896 IF4A1_ARATH (37-417): 4.7e-77: 246: 38.48		14332_ARATH (3-248): 2.24e-144: 405: 58.47
+	Hs
		684186 DDX6_HUMAN (29-425): 2.51e-75: 244: 36.59		1433Z_HUMAN (1-242): 8.34e-142: 398: 70.66
+	Hs
		684086 DDX6_HUMAN (29-425): 2.51e-75: 244: 36.59		1433T_HUMAN (1-238): 1e-107: 312: 71.85
+	Hs
		684092 DDX6_HUMAN (29-425): 2.51e-75: 244: 36.59		1433B_HUMAN (1-239): 3.42e-100: 293: 68.62
+	Hs
		684158 DDX6_HUMAN (29-425): 2.51e-75: 244: 36.59		1433G_HUMAN (1-242): 1.87e-98: 289: 65.16
+	Mm
		932541 DDX6_MOUSE (29-425): 1.35e-75: 245: 36.59		1433F_MOUSE (2-242): 1.73e-96: 284: 64.20