HitPredict

Interactor 1: VPS52 (Q8N1B4)
Vacuolar protein sorting-associated protein 52 homolog (SAC2 suppressor of actin mutations 2-like protein)
Gene: VPS52

Interactor 2: VPS54 (Q9P1Q0)
Vacuolar protein sorting-associated protein 54 (Hepatocellular carcinoma protein 8) (Tumor antigen HOM-HCC-8) (Tumor antigen SLP-8p)
Gene: VPS54

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

The method score is based on:

Property	Details
Experiments	27440922, 20685960, 25799061
Identification Methods	affinity chromatography technology, two hybrid, tandem affinity purification
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000938 - GARP complex GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0006896 - Golgi to vacuole transport GO:0007041 - lysosomal transport and 6 others more... GO:0016020 - membrane GO:0019905 - syntaxin binding GO:0032588 - trans-Golgi network membrane GO:0042147 - retrograde transport, endosome to Golgi GO:0048471 - perinuclear region of cytoplasm GO:0090119 - vesicle-mediated cholesterol transport
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	723
Hs

1	977

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024