Protein: PLAL1
Zinc finger protein PLAGL1 (Lost on transformation 1) (LOT-1) (Pleiomorphic adenoma-like protein 1) (Tumor suppressor ZAC)

Gene: PLAL1, PLAGL1
Organism: Homo sapiens
Interactions: 21
UniProt ID: Q9UM63

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1067833

EP300
Histone acetyltransferase p300

2

10

Small-scale

0.624

High

1061921

TLE5
TLE family member 5

2

3

High-throughput

0.606

High

186820

P73
Tumor protein p73

1

7

Small-scale

0.561

High

993811

UBC9
SUMO-conjugating enzyme UBC9

1

1

Small-scale

0.527

High

1225109

KANK2
KN motif and ankyrin repeat domain-containing protein 2

1

4

High-throughput

0.515

High

418513

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.513

High

813257

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.513

High

1014657

SMAD3
Mothers against decapentaplegic homolog 3

1

8

High-throughput

0.508

High

1459010

DAXX
Death domain-associated protein 6

1

0

Small-scale

0.504

High

297882

PIAS2
E3 SUMO-protein ligase PIAS2

1

6

Small-scale

0.501

High

414844

P53
Cellular tumor antigen p53

1

7

Small-scale

0.501

High

714520

PML
Protein PML

1

20

Small-scale

0.501

High

991461

SUMO1
Small ubiquitin-related modifier 1

1

1

Small-scale

0.501

High

1368530

CBP
CREB-binding protein

1

20

Small-scale

0.501

High

1369224

KAT2B
Histone acetyltransferase KAT2B

1

13

Small-scale

0.501

High

789595

PPARG
Peroxisome proliferator-activated receptor gamma

1

13

Small-scale

0.479

High

1110191

HDAC1
Histone deacetylase 1

1

5

Small-scale

0.479

High

417844

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.279

Low

505206

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

High-throughput

0.279

Low

1329482

KTAP2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2

1

0

High-throughput

0.279

Low

947313

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025