Interactor 1: RDHE2 (Q8N3Y7)
Epidermal retinol dehydrogenase 2 (EPHD-2) (RDH-E2) (EC 1.1.1.105) (Retinal short-chain dehydrogenase reductase 2) (retSDR2) (Short-chain dehydrogenase/reductase family 16C member 5)
Gene: SDR16C5

Interactor 2: RDHE2 (Q8N3Y7)
Epidermal retinol dehydrogenase 2 (EPHD-2) (RDH-E2) (EC 1.1.1.105) (Retinal short-chain dehydrogenase reductase 2) (retSDR2) (Short-chain dehydrogenase/reductase family 16C member 5)
Gene: SDR16C5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 36949045
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains adh_short~adh_short
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003714 - transcription corepressor activity
GO:0004745 - all-trans-retinol dehydrogenase (NAD+) activity
GO:0005634 - nucleus
and 9 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 309
Hs

1 309
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Ec
+ Dm
+ Dm
+ Ss
+ Hs
+ At
+ At
+ Hs

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Last updated: 15 Jul 2024